ZIC3 抗体 (AA 113-455)
Quick Overview for ZIC3 抗体 (AA 113-455) (ABIN7599755)
抗原
See all ZIC3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 113-455
-
原理
- Anti-ZIC3 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-ZIC3 Antibody Picoband® (ABIN7599755). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human ZIC3 recombinant protein (Position: N113-N455).
-
亚型
- IgG
-
-
anti-Zic Family Member 3 (ZIC3) (AA 182-274) antibody
ZIC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C1 unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 239-267) antibodyZIC3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB15116 unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 182-274) antibodyZIC3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 1-240) antibodyZIC3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 182-274) antibodyZIC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 178-189) antibodyVerified ZIC3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 93-142) antibodyZIC3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 1-240) antibodyZIC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zic Family Member 3 (ZIC3) (AA 4-32), (N-Term) antibodyZIC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15113 unconjugated
anti-Zic Family Member 3 (ZIC3) (N-Term) antibodyZIC3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aruga, J., Nagai, T., Tokuyama, T., Hayashizaki, Y., Okazaki, Y., Chapman, V. M., Mikoshiba, K. The mouse Zic gene family: homologues of the Drosophila pair-rule gene odd-paired. J. Biol. Chem. 271: 1043-1047, 1996. 2. Bedard, J. E. J., Purnell, J. D., Ware, S. M. Nuclear import and export signals are essential for proper cellular trafficking and function of ZIC3. Hum. Molec. Genet. 16: 187-198, 2007. 3. Burdine, R. D., Schier, A. F. Conserved and divergent mechanisms in left-right axis formation. Genes Dev. 14: 763-776, 2000. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- ZIC3 (Zic Family Member 3 (ZIC3))
-
别名
- ZIC3
-
背景
-
Synonyms: Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1, MTUS1, ATBP, ATIP, GK1, KIAA1288, MTSG1
Tissue Specificity: Ubiquitously expressed (at protein level). Highly expressed in brain. Down-regulated in ovarian carcinoma, pancreas carcinoma, colon carcinoma and head and neck squamous cell carcinoma (HNSCC). Isoform 1 is the major isoform in most peripheral tissues. Isoform 2 is abundant in most peripheral tissues. Isoform 3 is the major isoform in brain, female reproductive tissues, thyroid and heart. Within brain it is highly expressed in corpus callosum and pons. Isoform 6 is brain-specific, it is the major isoform in cerebellum and fetal brain.
Background: ZIC3 is a member of the Zinc finger of the cerebellum (ZIC) protein family. This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
-
分子量
- 56-60 kDa
-
基因ID
- 7547
-
UniProt
- O60481
抗原
-
