RAB3GAP1 抗体 (AA 109-810)
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- 抗原 See all RAB3GAP1 抗体
- RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))
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抗原表位
- AA 109-810
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAB3GAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- Anti-RAB3GAP1 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-RAB3GAP1 Antibody Picoband® (ABIN7599702). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human RAB3GAP1 recombinant protein (Position: N109-Q810).
- 亚型
- IgG
- Top Product
- Discover our top product RAB3GAP1 Primary Antibody
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anti-RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1) (AA 527-653), (Catalytic Subunit) antibody
RAB3GAP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1) (Internal Region) antibodyRAB3GAP1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1) (Internal Region) antibodyRAB3GAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abdel-Hamid, M. S., Abdel-Ghafar, S. F., Ismail, S. R., Desouky, L. M., Issa, M. Y., Effat, L. K., Zaki, M. S. Micro and Martsolf syndromes in 34 new patients: refining the phenotypic spectrum and further molecular insights. Clin. Genet. 98: 445-456, 2020. 2. Abdel-Salam, G. M. H., Hassan, N. A., Kayed, H. F., Aligianis, I. A. Phenotypic variability in Micro syndrome: report of new cases. Genet. Counsel. 18: 423-435, 2007. 3. Aligianis, I. A., Johnson, C. A., Gissen, P., Chen, D., Hampshire, D., Hoffmann, K., Maina, E. N., Morgan, N. V., Tee, L., Morton, J., Ainsworth, J. R., Horn, D., and 20 others. Mutations of the catalytic subunit of RAB3GAP cause Warburg Micro syndrome. Nature Genet. 37: 221-223, 2005. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))
- 别名
- RAB3GAP1 (RAB3GAP1 产品)
- 背景
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Synonyms: Ras GTPase-activating-like protein IQGAP2, IQGAP2
Tissue Specificity: Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine.
Background: Rab3 GTPase-activating protein catalytic subunit is an enzyme that in humans is encoded by the RAB3GAP1 gene. This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.
- 分子量
- 130 kDa
- 基因ID
- 22930
- UniProt
- Q15042
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