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TXNDC5 抗体 (AA 109-403)

This anti-TXNDC5 antibody is a 兔 多克隆 antibody detecting TXNDC5 in WB, ELISA, IHC, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599699
发货至: 中国

Quick Overview for TXNDC5 抗体 (AA 109-403) (ABIN7599699)

抗原

See all TXNDC5 抗体
TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

适用

  • 51
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  • 3
人, 小鼠, 大鼠

宿主

  • 41
  • 7
  • 3

克隆类型

  • 46
  • 5
多克隆

标记

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This TXNDC5 antibody is un-conjugated

应用范围

  • 44
  • 19
  • 14
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  • 9
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  • 3
  • 2
  • 2
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 7
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    • 2
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    • 1
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    AA 109-403

    原理

    Anti-TXNDC5 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-TXNDC5 Antibody Picoband® (ABIN7599699). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TXNDC5 recombinant protein (Position: M109-R403).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Knoblach, B., Keller, B. O., Groenendyk, J., Aldred, S., Zheng, J., Lemire, B. D., Li, L., Michalak, M. ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins. Molec. Cell. Proteomics 2: 1104-1119, 2003. 2. Nissom, P. M., Lo, S. L., Lo, J. C. Y., Ong, P. F., Lim, J. W. E., Ou, K., Liang, R. C., Seow, T. K., Chung, M. C. M. Hcc-2, a novel mammalian ER thioredoxin that is differentially expressed in hepatocellular carcinoma. FEBS Lett. 580: 2216-2226, 2006. 3. Sullivan, D. C., Huminiecki, L., Moore, J. W., Boyle, J. J., Poulsom, R., Creamer, D., Barker, J., Bicknell, R. EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor. J. Biol. Chem. 278: 47079-47088, 2003.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

    别名

    TXNDC5

    背景

    Synonyms: Protein phosphatase 1 regulatory subunit 14A,17 kDa PKC-potentiated inhibitory protein of PP1,Protein kinase C-potentiated inhibitor protein of 17 kDa,CPI-17,PPP1R14A,CPI17, PPP1INL,

    Tissue Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .

    Background: Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.

    分子量

    50-55 kDa

    基因ID

    81567

    途径

    Cell RedoxHomeostasis
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