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KIF1A 抗体 (AA 1079-1628)

KIF1A 适用: 小鼠, 人, 大鼠 ELISA, WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599679
发货至: 中国
  • 抗原 See all KIF1A 抗体
    KIF1A (Kinesin Family Member 1A (KIF1A))
    抗原表位
    • 5
    • 2
    AA 1079-1628
    适用
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 人, 大鼠
    宿主
    • 9
    • 1
    克隆类型
    • 9
    • 1
    多克隆
    标记
    • 6
    • 2
    • 1
    • 1
    This KIF1A antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 2
    • 2
    • 2
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    原理
    Anti-KIF1A Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-KIF1A Antibody Picoband® (ABIN7599679). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human KIF1A recombinant protein (Position: H1079-Y1628).
    亚型
    IgG
    Top Product
    Discover our top product KIF1A Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chiba, K., Takahashi, H., Chen, M., Obinata, H., Arai, S., Hashimoto, K., Oda, T., McKenney, R. J., Niwa, S. Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors. Proc. Nat. Acad. Sci. 116: 18429-18434, 2019. 2. Citterio, A., Arnoldi, A., Panzeri, E., Merlini, L., D'Angelo, M. G., Musumeci, O., Toscano, A., Bondi, A., Martinuzzi, A., Bresolin, N., Bassi, M. T. Variants in KIF1A gene in dominant and sporadic forms of hereditary spastic paraparesis. J. Neurol. 262: 2684-2690, 2015. 3. Erlich, Y., Edvardson, S., Hodges, E., Zenvirt, S., Thekkat, P., Shaag, A., Dor, T., Hannon, G. J., Elpeleg, O. Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis. Genome Res. 21: 658-664, 2011.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    KIF1A (Kinesin Family Member 1A (KIF1A))
    别名
    KIF1A (KIF1A 产品)
    背景

    Synonyms: S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin, SAG,

    Tissue Specificity: Retina and pineal gland.

    Background: Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded by the KIF1A gene. The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    分子量
    191 kDa
    基因ID
    547
    UniProt
    Q12756
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