CDK13 抗体 (AA 1052-1338)
Quick Overview for CDK13 抗体 (AA 1052-1338) (ABIN7599667)
抗原
See all CDK13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1052-1338
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原理
- Anti-CDK13 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CDK13 Antibody Picoband® (ABIN7599667). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CDK13 recombinant protein (Position: D1052-N1338).
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亚型
- IgG
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anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-324) antibody
CDK13 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1B3-1B11 unconjugated
anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-90) antibodyCDK13 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-170) antibodyCDK13 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 13 (CDK13) antibodyCDK13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 13 (CDK13) (Internal Region) antibodyCDK13 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hamilton, M. J., Caswell, R. C., Canham, N., Cole, T., Firth, H. V., Foulds, N., Heimdal, K., Hobson, E., Houge, G., Joss, S., Kumar, D., Lampe, A. K. Heterozygous mutations affecting the protein kinase domain of CDK13 cause a syndromic form of developmental delay and intellectual disability. J. Med. Genet. 55: 28-38, 2018. 2. Lapidot-Lifson, Y., Patinkin, D., Prody, C. A., Ehrlich, G., Seidman, S., Ben-Aziz, R., Benseler, F., Eckstein, F., Zakut, H., Soreq, H. Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis. Proc. Nat. Acad. Sci. 89: 579-583, 1992. 3. Sifrim, A., Hitz, M.-P., Wilsdon, A., Breckpot, J., Al Turki, S. H., Thienpont, B., McRae, J., Fitzgerald, T. W., Singh, T., Swaminathan, G. J., Prigmore, E., Rajan, D., and 63 others. Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing. Nature Genet. 48: 1060-1065, 2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CDK13 (Cyclin-Dependent Kinase 13 (CDK13))
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别名
- CDK13
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背景
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Synonyms: Loricrin, LOR, LRN
Tissue Specificity: Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.
Background: Cyclin dependent kinase 13 is an enzyme that in humans is encoded by the CDK13 gene. The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.
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分子量
- 185-190 kDa
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基因ID
- 8621
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UniProt
- Q14004
抗原
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