YTHDC2 抗体 (AA 105-1231)
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北京 101111
Quick Overview for YTHDC2 抗体 (AA 105-1231) (ABIN7599661)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 105-1231
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原理
- Anti-YTHDC2 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-YTHDC2 Antibody (ABIN7599661). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human YTHDC2 recombinant protein (Position: K105-K1231).
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亚型
- IgG
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anti-YTH Domain Containing 2 (YTHDC2) antibody
KD Validated YTHDC2 适用: 小鼠 WB, FACS 宿主: 兔 Monoclonal 25GB4785 unconjugated Recombinant Antibody
anti-YTH Domain Containing 2 (YTHDC2) (AA 1131-1430) antibodyYTHDC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- YTHDC2 (YTH Domain Containing 2 (YTHDC2))
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别名
- YTHDC2
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背景
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Synonyms: One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B
Tissue Specificity: Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.
Background: YTH domain containing 2 is a protein that in humans is encoded by the YTHDC2 gene. This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
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分子量
- 175 kDa
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基因ID
- 64848
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UniProt
- Q9H6S0
抗原
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