DIAPH1 抗体 (AA 1039-1153)
Quick Overview for DIAPH1 抗体 (AA 1039-1153) (ABIN7599652)
抗原
See all DIAPH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1039-1153
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原理
- Anti-DIAPH1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DIAPH1 Antibody Picoband® (ABIN7599652). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DIAPH1 recombinant protein (Position: D1039-Q1153).
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亚型
- IgG
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anti-Diaphanous Homolog 1 (DIAPH1) (C-Term) antibody
DIAPH1 适用: 人, 小鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) antibodyDIAPH1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (N-Term) antibodyDIAPH1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (AA 1-404) antibodyDIAPH1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (AA 389-583) antibodyDIAPH1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (AA 921-1024) antibodyDIAPH1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (AA 18-52), (N-Term) antibodyDIAPH1 适用: 人 WB 宿主: 兔 Polyclonal RB30760 unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (AA 1-404) antibodyDIAPH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (AA 921-1024) antibodyDIAPH1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Diaphanous Homolog 1 (DIAPH1) (AA 1-404) antibodyDIAPH1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Al-Maawali, A., Barry, B. J., Rajab, A., El-Quessny, M., Seman, A., Coury, S. N., Barkovich, A. J., Yang, E., Walsh, C. A., Mochida, G. H., Stoler, J. M. Novel loss-of-function variants in DIAPH1 associated with syndromic microcephaly, blindness, and early onset seizures. Am. J. Med. Genet. 170A: 435-440, 2016. 2. Carreira, S., Goodall, J., Denat, L., Rodriguez, M., Nuciforo, P., Hoek, K. S., Testori, A., Larue, L., Goding, C. R. Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev. 20: 3426-3439, 2006. 3. Ercan-Sencicek, A. G., Jambi, S., Franjic, D., Nishimura, S., Li, M., El-Fishawy, P., Morgan, T. M., Sanders, S. J., Bilguvar, K., Suri, M., Johnson, M. H., Gupta, A. R., Yuksel, Z., Mane, S., Grigorenko, E., Picciotto, M., Alberts, A. S., Gunel, M., Sestan, N., State, M. W. Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans. Europ. J. Hum. Genet. 23: 165-172, 2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
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别名
- DIAPH1
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背景
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Synonyms: Adrenocorticotropic hormone receptor,ACTH receptor,ACTH-R,Adrenocorticotropin receptor,Melanocortin receptor 2,MC2-R,MC2R,ACTHR,
Tissue Specificity: Melanocytes and corticoadrenal tissue.
Background: Protein diaphanous homolog 1 is a protein that in humans is encoded by the DIAPH1 gene. This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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分子量
- 150 kDa
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基因ID
- 1729
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UniProt
- O60610
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途径
- Sensory Perception of Sound
抗原
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