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Ninein 抗体 (AA 1023-2090)

NIN 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599645
发货至: 中国
  • 抗原 See all Ninein (NIN) 抗体
    Ninein (NIN) (Ninein (GSK3B Interacting Protein) (NIN))
    抗原表位
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1023-2090
    适用
    人, 小鼠, 大鼠
    宿主
    • 12
    克隆类型
    • 12
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    This Ninein antibody is un-conjugated
    应用范围
    • 7
    • 5
    • 5
    • 3
    • 3
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    Anti-Ninein/NIN Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-Ninein/NIN Antibody Picoband® (ABIN7599645). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Ninein/NIN recombinant protein (Position: Q1023-H2090).
    亚型
    IgG
    Top Product
    Discover our top product NIN Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chen, C.-H., Howng, S.-L., Cheng, T.-S., Chou, M.-H., Huang, C.-Y., Hong, Y.-R. Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle. Biochem. Biophys. Res. Commun. 308: 975-983, 2003. 2. Chou, C. H., Loh, J. K., Yang, M. C., Lin, C. C., Hong, M. C., Cho, C. L., Chou, A. K., Wang, C. H., Lieu, A. S., Howng, S. L., Hsu, C. M., Hong, Y. R. AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1. Cell Cycle 14: 2764-2776, 2015. 3. Dauber, A., LaFranchi, S. H., Maliga, Z., Lui, J. C., Moon, J. E., McDeed, C., Henke, K., Zonana, J., Kingman, G. A., Pers, T. H., Baron, J., Rosenfeld, R. G., Hirschhorn, J. N., Harris, M. P., Hwa, V. Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein. J. Clin. Endocr. Metab. 97: E2140-E2151, 2012. Note: Electronic Article.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    Ninein (NIN) (Ninein (GSK3B Interacting Protein) (NIN))
    别名
    NIN (NIN 产品)
    背景

    Synonyms: Endoglin, Cell surface MJ7/18 antigen, CD105, Eng, Edg,

    Background: Ninein is a protein that in humans is encoded by the NIN gene. This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.

    分子量
    260 kDa
    基因ID
    51199
    UniProt
    Q8N4C6
    途径
    Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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