TNNI3K 抗体 (AA 102-783)
Quick Overview for TNNI3K 抗体 (AA 102-783) (ABIN7599644)
抗原
See all TNNI3K 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 102-783
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原理
- Anti-TNNI3K Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-TNNI3K Antibody Picoband® (ABIN7599644). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TNNI3K recombinant protein (Position: F102-Q783).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fan, L.-L., Huang, H., Jin, J.-Y., Li, J.-J., Chen, Y.-Q., Zhao, S.-P., Xiang, R. Whole exome sequencing identifies a novel mutation (c.333+2T-C) of TNNI3K in a Chinese family with dilated cardiomyopathy and cardiac conduction disease. Gene 648: 63-67, 2018. 2. Lai, Z.-F., Chen, Y.-Z., Feng, L.-P., Meng, X.-M., Ding, J.-F., Wang, L.-Y., Ye, J., Li, P., Cheng, X.-S., Kitamoto, Y., Monzen, K., Komuro, I., Sakaguchi, N., Kim-Mitsuyama, S. Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury. Am. J. Physiol. Heart Circ. Physiol. 295: H708-H716, 2008. Note: Erratum: Am. J. Physiol. Heart Circ. Physiol. 295: H1815 only, 2008. 3. Patterson, M., Barske, L., Van Handel, B., Rau, C. D., Gan, P., Sharma, A., Parikh, S., Denholtz, M., Huang, Y., Yamaguchi, Y., Shen, H., Allayee, H., Crump, J. G., Force, T. I., Lien, C.-L., Makita, T., Lusis, A. J., Kumar, S. R., Sucov, H. M. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genet. 49: 1346-1353, 2017. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TNNI3K (TNNI3 Interacting Kinase (TNNI3K))
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别名
- TNNI3K
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背景
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Synonyms: Max dimerization protein 1, Max dimerizer 1, Protein MAD, MXD1, MAD
Background: TNNI3 interacting kinase is a protein that in humans is encoded by the TNNI3K gene. This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.
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分子量
- 110 kDa
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基因ID
- 51086
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UniProt
- Q59H18
抗原
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