MAP1B 抗体 (AA 102-1849)
Quick Overview for MAP1B 抗体 (AA 102-1849) (ABIN7599633)
抗原
See all MAP1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 102-1849
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原理
- Anti-MAP1B Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MAP1B Antibody Picoband® (ABIN7599633). Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MAP1B recombinant protein (Position: H102-R1849). Human MAP1B shares 89.9% and 89.2% amino acid (aa) sequence identity with mouse and rat MAP1B, respectively.
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亚型
- IgG
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anti-Microtubule-Associated Protein 1B (MAP1B) (AA 2203-2464) antibody
MAP1B 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1B (MAP1B) (AA 1820-2100) antibodyMAP1B 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1B (MAP1B) (AA 2207-2468) antibodyMAP1B 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1B (MAP1B) (Internal Region) antibodyMAP1B 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1B (MAP1B) (AA 451-550) antibodyMAP1B 适用: 人, 小鼠, 大鼠 ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1B (MAP1B) (AA 451-550) antibody (FITC)MAP1B 适用: 人, 小鼠, 大鼠 FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
anti-Microtubule-Associated Protein 1B (MAP1B) antibodyMAP1B 适用: 人, 大鼠, Cow IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
Immunofluorescence, 5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Allen, E., Ding, J., Wang, W., Pramanik, S., Chou, J., Yau, V., Yang, Y. Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival. Nature 438: 224-228, 2005. 2. Cui, L., Zheng, J., Zhao, Q., Chen, J.-R., Liu, H., Peng, G., Wu, Y., Chen, C., He, Q., Shi, H., Yin, S., Friedman, R. A., Chen, Y., Guan, M.-X. Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss. JCI Insight 5: e136046, 2020. 3. Edelmann, W., Zervas, M., Costello, P., Roback. L., Fischer, I., Hammarback, J. A., Cowan, N., Davies, P., Wainer, B., Kucherlapati, R. Neuronal abnormalities in microtubule-associated protein 1B mutant mice. Proc. Nat. Acad. Sci. 93: 1270-1275, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MAP1B (Microtubule-Associated Protein 1B (MAP1B))
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别名
- MAP1B
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背景
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Synonyms: MAP1B, Microtubule-associated protein 1B, MAP-1B [Cleaved into: MAP1B heavy chain, MAP1 light chain LC1]
Background: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system.
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分子量
- 271 kDa
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基因ID
- 4131
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UniProt
- P46821
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途径
- Microtubule Dynamics, Regulation of Cell Size
抗原
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