SEC31A 抗体 (AA 101-806)
Quick Overview for SEC31A 抗体 (AA 101-806) (ABIN7599630)
抗原
See all SEC31A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-806
-
原理
- Anti-SEC31A Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-SEC31A Antibody Picoband® (ABIN7599630). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SEC31A recombinant protein (Position: Y101-K806).
-
亚型
- IgG
-
-
anti-SEC31 Homolog A (SEC31A) (AA 429-571) antibody
SEC31A 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 5D12C6 unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 335-503) antibodySEC31A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 473-502) antibodySEC31A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41562 unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 110-159) antibodySEC31A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (AA 300-500) antibodySEC31A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (N-Term) antibodySEC31A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SEC31 Homolog A (SEC31A) (N-Term) antibodySEC31A 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Halperin, D., Kadir, R., Perez, Y., Drabkin, M., Yogev, Y., Wormser, O., Berman, E. M., Eremenko, E., Rotblat, B., Shorer, Z., Gradstein, L., Shelef, I., Birk, R., Abdu, U., Flusser, H., Birk, O. S. SEC31A mutation affects ER homeostasis, causing a neurologic syndrome. J. Med. Genet. 56: 139-148, 2019. 2. Jin, L., Pahuja, K. B., Wickliffe, K. E., Gorur, A., Baumgartel, C., Schekman, R., Rape, M. Ubiquitin-dependent regulation of COPII coat size and function. Nature 482: 495-500, 2012. 3. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Oharo, O. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 5: 355-364, 1998. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- SEC31A (SEC31 Homolog A (SEC31A))
-
别名
- SEC31A
-
背景
-
Synonyms: C-type lectin domain family 9 member A, CLEC9A, UNQ9341/PRO34046
Tissue Specificity: In peripheral blood highly restricted on the surface of BDCA31+ dendritic cells and on a small subset of CD14+ and CD16- monocytes.
Background: Protein transport protein Sec31A is a protein that in humans is encoded by the SEC31A gene. The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
-
分子量
- 133 kDa
-
基因ID
- 22872
-
UniProt
- O94979
-
途径
- ER-Nucleus Signaling
抗原
-
