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MTDH 抗体 (AA 101-270)

This anti-MTDH antibody is a 小鼠单克隆 antibody detecting MTDH in WB, IHC 和 FACS. Suitable for 人.

产品编号 ABIN7599627

发货至: 中国

Quick Overview for MTDH 抗体 (AA 101-270) (ABIN7599627)

抗原

See all MTDH 抗体

MTDH (Metadherin (MTDH))

适用

57
19
8
2
2
1
1
1
1
1

人

宿主

小鼠

克隆类型

单克隆

标记

36
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This MTDH antibody is un-conjugated

应用范围

48
17
17
13
13
12
11
10
10
10
6
2

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

2E5G3

Discover our top product MTDH Primary Antibody

抗原表位
16

4

3

2

2

2

2

2

2

2

1

1

1
AA 101-270

原理

Anti-LYRIC Antibody Picoband® (monoclonal, 2E5G3)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-LYRIC Antibody Picoband® (monoclonal, 2E5G3) (ABIN7599627). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human LYRIC recombinant protein (Position: D101-Q270). Human LYRIC shares 94% amino acid (aa) sequence identity with both mouse and rat LYRIC.

亚型

IgG2b
anti-Metadherin (MTDH) antibody
MTDH 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Metadherin (MTDH) (AA 101-270) antibody
MTDH 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Metadherin (MTDH) antibody
MTDH 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Metadherin (MTDH) (AA 1-582) antibody
MTDH 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Metadherin (MTDH) (AA 1-582) antibody
MTDH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Metadherin (MTDH) antibody
MTDH 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2F11C3 unconjugated

anti-Metadherin (MTDH) (AA 101-270) antibody
MTDH 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Metadherin (MTDH) (AA 1-260) antibody
MTDH 适用: 人 IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated

anti-Metadherin (MTDH) (AA 131-230) antibody
MTDH 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Metadherin (MTDH) antibody
MTDH 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2F11C3 unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Brown DM, Ruoslahti E (April 2004). "Metadherin, a cell surface protein in breast tumors that mediates lung metastasis". Cancer Cell 5 (4): 365-74. 2. Hu G, Chong RA, Yang Q, Wei Y, Blanco MA, Li F, Reiss M, Au JL, Haffty BG, Kang Y (January 2009). "MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer". Cancer Cell 15 (1): 9-20. 3. Yoo BK, Emdad L, Lee SG, Su ZZ, Santhekadur P, Chen D, Gredler R, Fisher PB, Sarkar D (January 2011)."Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology".Pharmacol Ther 130 (1): 1-8.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

MTDH (Metadherin (MTDH))

别名

MTDH

背景

Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115
Background: MTDH (Metadherin), also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene. AEG-1 is involved in HIF-1alpha mediated angiogenesis. AEG-1 also interacts with SND1 and involved in RNA-induced silencing complex (RISC) and plays very important role in RISC and miRNA functions. AEG-1 induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor (LSF/TFCP2) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9). AEG-1 acts as an oncogene in melanoma, malignant glioma, breast cancer and hepatocellular carcinoma. It is highly expressed in these cancers and helps in progression and development of these cancers. It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells.

分子量

85 kDa

基因ID

92140

途径

Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization

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