DOCK1 抗体 (AA 100-1732)
Quick Overview for DOCK1 抗体 (AA 100-1732) (ABIN7599615)
抗原
See all DOCK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-1732
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原理
- Anti-DOCK180/DOCK1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DO/DOCK1 Antibody Picoband® (ABIN7599615). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DOCK180/DOCK1 recombinant protein (Position: S100-T1732).
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亚型
- IgG
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anti-Dedicator of Cytokinesis 1 (DOCK1) (AA 1676-1865) antibody
DOCK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (C-Term) antibodyDOCK1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (AA 698-803) antibodyDOCK1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (C-Term) antibodyDOCK1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (AA 1645-2186) antibodyDOCK1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (C-Term) antibodyVerified DOCK1 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 1 (DOCK1) (AA 1200-1435) antibodyDOCK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Humann
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cote, J.-F., Vuori, K. Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J. Cell Sci. 115: 4901-4913, 2002. 2. Gross, M. B. Personal Communication. Baltimore, Md. 8/31/2016. 3. Hasegawa, H., Kiyokawa, E., Tanaka, S., Nagashima, K., Gotoh, N., Shibuya, M., Kurata, T., Matsuda, M. DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the membrane. Molec. Cell Biol. 16: 1770-176, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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别名
- DOCK1
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背景
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Synonyms: Tumor necrosis factor-inducible gene 6 protein,Hyaluronate-binding protein,TNF-stimulated gene 6 protein,TSG-6,Tumor necrosis factor alpha-induced protein 6,TNF alpha-induced protein 6,TNFAIP6,TSG6,
Tissue Specificity: Found in the synovial fluid of patients with rheumatoid arthritis. .
Background: Dock180, (Dedicator of cytokinesis) also known as DOCK1, is a large (~180 kDa) protein involved in intracellular signalling networks. This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.
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分子量
- 215 kDa
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基因ID
- 1793
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UniProt
- Q14185
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途径
- Signaling of Hepatocyte Growth Factor Receptor
抗原
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