UBR2 抗体 (AA 10-664)
Quick Overview for UBR2 抗体 (AA 10-664) (ABIN7599610)
抗原
See all UBR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 10-664
-
原理
- Anti-UBR2 Picoband® Antibody (monoclonal, 2G10)
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-UBR2 Picoband® Antibody (monoclonal, 2G10) (ABIN7599610). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human UBR2 recombinant protein (Position: Q10-A664).
-
亚型
- IgG2a
-
-
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibody
UBR2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4G4 unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 101-439) antibodyUBR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) antibodyUBR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibodyUBR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (Internal Region) antibodyVerified UBR2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-439) antibodyUBR2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
1. Kwon, Y. T., Xia, Z., An, J. Y., Tasaki, T., Davydov, I. V., Seo, J. W., Sheng, J., Xie, Y., Varshavsky, A. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Molec. Cell. Biol. 23: 8255-8271, 2003. 2. Nagase, T., Ishikawa, K., Nakajima, D., Ohira, M., Seki, N., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 4: 141-150, 1997. 3. Yin, J., Kwon, Y. T., Varshavsky, A., Wang, W. RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Hum. Molec. Genet. 13: 2421-2430, 2004. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
-
别名
- UBR2
-
背景
-
Synonyms: Tubulin beta chain, Tubulin beta-5 chain, TUBB, TUBB5, OK/SW-cl.56
Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Background: E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.
-
分子量
- 202 kDa
-
基因ID
- 23304
抗原
-
