UBR2 抗体 (AA 10-664)
Quick Overview for UBR2 抗体 (AA 10-664) (ABIN7599609)
抗原
See all UBR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-664
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原理
- Anti-UBR2 Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-UBR2 Picoband® Antibody (ABIN7599609). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human UBR2 recombinant protein (Position: Q10-A664).
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亚型
- IgG
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anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibody
UBR2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4G4 unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 101-439) antibodyUBR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) antibodyUBR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibodyUBR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (Internal Region) antibodyVerified UBR2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-439) antibodyUBR2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kwon, Y. T., Xia, Z., An, J. Y., Tasaki, T., Davydov, I. V., Seo, J. W., Sheng, J., Xie, Y., Varshavsky, A. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Molec. Cell. Biol. 23: 8255-8271, 2003. 2. Nagase, T., Ishikawa, K., Nakajima, D., Ohira, M., Seki, N., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 4: 141-150, 1997. 3. Yin, J., Kwon, Y. T., Varshavsky, A., Wang, W. RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Hum. Molec. Genet. 13: 2421-2430, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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别名
- UBR2
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背景
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Synonyms: E3 ubiquitin-protein ligase UBR2, N-recognin-2, RING-type E3 ubiquitin transferase UBR2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II, UBR2, C6orf133, KIAA0349
Tissue Specificity: Expressed ubiquitously.
Background: E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.
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分子量
- 201 kDa
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基因ID
- 23304
抗原
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