BCL11B 抗体 (AA 10-628)
Quick Overview for BCL11B 抗体 (AA 10-628) (ABIN7599607)
抗原
See all BCL11B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-628
-
原理
- Anti-BCL11B Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-BCL11B Antibody Picoband® (ABIN7599607). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human BCL11B recombinant protein (Position: Q10-A628).
-
亚型
- IgG
-
-
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) (AA 1-150) antibody
BCL11B 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 1F8G8 unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) antibodyBCL11B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) (AA 1-150) antibodyBCL11B 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1F8H9 unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) (Internal Region) antibodyBCL11B 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) (AA 395-444) antibodyBCL11B 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) antibodyBCL11B 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) antibodyBCL11B 适用: 小鼠, 大鼠 IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) antibodyBCL11B 适用: 小鼠, 大鼠 IHC, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) (AA 500-550) antibodyBCL11B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) (C-Term) antibodyBCL11B 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, Pig, 斑马鱼, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Arlotta, P., Molyneaux, B. J., Chen, J., Inoue, J., Kominami, R., Macklis, J. D. Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo. Neuron 45: 207-221, 2005. 2. Avram, D., Fields, A., Top, K. P. O., Nevrivy, D. J., Ishmael, J. E., Leid, M. Isolation of a novel family of C2H2 zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. J. Biol. Chem. 275: 10315-10322, 2000. 3. Chen, B., Wang, S. S., Hattox, A. M., Rayburn, H., Nelson, S. B., McConnell, S. K. The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortex. Proc. Nat. Acad. Sci. 105: 11382-11387, 2008. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
-
别名
- BCL11B
-
背景
-
Synonyms: Flap endonuclease 1, FEN-1, DNase IV, Flap structure-specific endonuclease 1, Maturation factor 1, MF1, hFEN-1
Tissue Specificity: Predominantly expressed in the liver (PubMed:11099417, PubMed:11452359). Low expression levels in the small intestine and colon (PubMed:11099417). Very low levels in other tissues, including brain, heart and spleen (PubMed:11452359).
Background: B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene. This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
-
分子量
- 116 kDa
-
基因ID
- 64919
-
UniProt
- Q9C0K0
抗原
-
