TFB2M 抗体 (AA 10-386)
Quick Overview for TFB2M 抗体 (AA 10-386) (ABIN7599599)
抗原
See all TFB2M 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-386
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原理
- Anti-TFB2M Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-TFB2M Antibody Picoband® (ABIN7602101). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TFB2M recombinant protein (Position: R10-K386). Human TFB2M shares 53.2% and 54.8% amino acid (aa) sequence identity with mouse and rat TFB2M, respectively.
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亚型
- IgG
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anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 297-396) antibody
TFB2M 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 297-396) antibodyTFB2M 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 1-396) antibodyTFB2M 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (Internal Region) antibodyVerified TFB2M 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 101-150) antibodyTFB2M 适用: 人, 大鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 368-396), (C-Term) antibodyTFB2M 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22408 unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 30-108) antibodyTFB2M 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (C-Term) antibodyVerified TFB2M 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (Internal Region) antibodyVerified TFB2M 适用: 大鼠, 小鼠 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (N-Term) antibodyTFB2M 适用: 人, 大鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cotney, J., McKay, S. E., Shadel, G. S. Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness. Hum. Molec. Genet. 18: 2670-2682, 2009. 2. Falkenberg, M., Gaspari, M., Rantanen, A., Trifunovic, A., Larsson, N.-G., Gustafsson, C. M. Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. Nature Genet. 31: 289-294, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
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别名
- TFB2M
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Dimethyladenosine transferase 2, transcription factor B2, mitochondrial is an enzyme that in humans is encoded by the TFB2M gene. S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA atthe conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction withPOLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, itactivates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity
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分子量
- 38 kDa
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基因ID
- 64216
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UniProt
- Q9H5Q4
抗原
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