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USP10 抗体 (AA 1-798)

This anti-USP10 antibody is a 兔 多克隆 antibody detecting USP10 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599550
发货至: 中国

Quick Overview for USP10 抗体 (AA 1-798) (ABIN7599550)

抗原

See all USP10 抗体
USP10 (Ubiquitin Specific Peptidase 10 (USP10))

适用

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人, 小鼠, 大鼠

宿主

  • 60
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克隆类型

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多克隆

标记

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This USP10 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1-798

    原理

    Anti-USP10 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-USP10 Antibody Picoband® (ABIN7599550). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human USP10 recombinant protein (Position: M1-L798).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Gross, M. B. Personal Communication. Baltimore. Md. 1/25/2021. 2. Lim, R., Sugino, T., Nolte, H., Andrade, J., Zimmermann, B., Shi, C., Doddaballapur, A., Ong, Y. T., Wilhelm, K., Fasse, J. W. D., Ernst, A., Kaulich, M., Husnjak, K., Boettger, T., Guenther, S., Braun, T., Kruger, M., Benedito, R., Dikic, I., Potente, M. Deubiquitinase USP10 regulates Notch signaling in the endothelium. Science 364: 188-193, 2019. 3. Liu, J., Xia, H., Kim, M., Xu, L., Zhang, L., Cai, Y., Norberg, H. V., Zhang, T., Furuya, T., Jin, M., Zhu, Z., Wang, H., Yu, J., Li, Y., Hao, Y., Choi, A., Ke, H., Ma, D., Yuan, J. Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell 147: 223-234, 2011.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    USP10 (Ubiquitin Specific Peptidase 10 (USP10))

    别名

    USP10

    背景

    Synonyms: S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin, SAG,

    Tissue Specificity: Retina and pineal gland.

    Background: Ubiquitin specific peptidase 10, also known as USP10, is an enzyme which in humans is encoded by the USP10 gene. Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene.

    分子量

    110 kDa, 130 kDa

    基因ID

    9100

    UniProt

    Q14694
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