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slc25a13 抗体 (AA 1-643)

This anti-slc25a13 antibody is a 兔 多克隆 antibody detecting slc25a13 in WB, IHC, ELISA, IF, ICC 和 FACS. Suitable for 人 和 大鼠.
产品编号 ABIN7599512
发货至: 中国

Quick Overview for slc25a13 抗体 (AA 1-643) (ABIN7599512)

抗原

See all slc25a13 抗体
slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This slc25a13 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-643

    原理

    Anti-Citrin/SLC25A13 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Citrin/SLC25A13 Antibody Picoband® (ABIN7599512). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Citrin/SLC25A13 recombinant protein (Position: M1-A643).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Fiermonte, G., Soon, D., Chaudhuri, A., Paradies, E., Lee, P. J., Krywawych, S., Palmieri, F., Lachmann, R. H. An adult with type 2 citrullinemia presenting in Europe. (Letter) New Eng. J. Med. 358: 1408-1409, 2008. 2. Kobayashi, K., Sinasac, D. S., Iijima, M., Boright, A. P., Begum, L., Lee, J. R., Yasuda, T., Ikeda, S., Hirano, R., Terazono, H., Crackower, M. A., Kondo, I., Tsui, L.-C., Scherer, S. W., Saheki, T. The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein. Nature Genet. 22: 159-163, 1999. 3. Ohura, T., Kobayashi, K., Tazawa, Y., Nishi, I., Abukawa, D., Sakamoto, O., Iinuma, K., Saheki, T. Neonatal presentation of adult-onset type II citrullinemia. Hum. Genet. 108: 87-90, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))

    别名

    SLC25A13

    背景

    Synonyms: Methyl-CpG-binding domain protein 4, Methyl-CpG-binding endonuclease 1, Methyl-CpG-binding protein MBD4, Mismatch-specific DNA N-glycosylase, MBD4, MED1

    Background: Citrin also known as solute carrier family 25, member 13 (citrin) or SLC25A13 is a protein which in humans is encoded by the SLC25A13 gene. This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    70 kDa

    基因ID

    10165

    途径

    Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport
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