GRHL2 抗体 (AA 1-625)
Quick Overview for GRHL2 抗体 (AA 1-625) (ABIN7599505)
抗原
See all GRHL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-625
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原理
- Anti-GRHL2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GRHL2 Antibody Picoband® (ABIN7599505). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRHL2 recombinant protein (Position: M1-I625).
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亚型
- IgG
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anti-Grainyhead-Like 2 (GRHL2) (AA 1-625) antibody
GRHL2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Grainyhead-Like 2 (GRHL2) (AA 1-265) antibodyGRHL2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 2 (GRHL2) (C-Term) antibodyGRHL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 小鸡, Bat, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 2 (GRHL2) (Middle Region) antibodyGRHL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 2 (GRHL2) (AA 111-210) antibodyGRHL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Grainyhead-Like 2 (GRHL2) (AA 80-250) antibodyGRHL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Grainyhead-Like 2 (GRHL2) (Middle Region) antibodyGRHL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, W., Dong, Q., Shin, K.-H., Kim, R. H., Oh, J.-E., Park, N.-H., Kang, M. K. Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5-prime-CpG island in normal human keratinocytes. J. Biol. Chem. 285: 40852-40863, 2010. 2. Han, Y., Mu, Y., Li, X., Xu, P., Tong, J., Liu, Z., Ma, T., Zeng, G., Yang, S., Du, J., Meng, A. Grhl2 deficiency impairs otic development and hearing ability in a zebrafish model of the progressive dominant hearing loss DFNA28. Hum. Molec. Genet. 20: 3213-3226, 2011. 3. Jacobs, J., Atkins, M., Davie, K., Imrichova, H., Romanelli, L., Christiaens, V., Hulselmans, G., Potier, D., Wouters, J., Taskiran, I. I., Paciello, G., Gonzalez-Blas, C. B., Koldere, D., Aibar, S., Halder, G., Aerts, S. The transcription factor grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes. Nature Genet. 50: 1011-1020, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GRHL2 (Grainyhead-Like 2 (GRHL2))
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别名
- GRHL2
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背景
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Synonyms: Olfactomedin-4, OLM4, Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein, hGC-1, hOLfD, OLFM4, GW112, UNQ362, PRO698
Tissue Specificity: Expressed during myeloid lineage development. Much higher expression in bone marrow neutrophils than in peripheral blood neutrophils (at protein level). Strongly expressed in the prostate, small intestine and colon and moderately expressed in the bone marrow and stomach. Overexpressed in some pancreatic cancer tissues.
Background: The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28).
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分子量
- 71 kDa
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基因ID
- 79977
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途径
- Tube Formation
抗原
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