FBXW8 抗体 (AA 1-598)
Quick Overview for FBXW8 抗体 (AA 1-598) (ABIN7599492)
抗原
See all FBXW8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-598
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原理
- Anti-FBXW8 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-FBXW8 Antibody (ABIN7599492). Tested in WB, ELISA applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FBXW8 recombinant protein (Position: M1-V598). Human FBXW8 shares 78.5% and 77.4% amino acid (aa) sequence identity with mouse and rat FBXW8, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
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别名
- FBXW8
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背景
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Synonyms: FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6, F-box/WD repeat-containing protein 8, F-box and WD-40 domain-containing protein 8, F-box only protein 29
Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
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分子量
- 67 kDa
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基因ID
- 26259
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UniProt
- Q8N3Y1
抗原
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