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Plastin 3 抗体 (AA 1-580)

This anti-Plastin 3 antibody is a 兔 多克隆 antibody detecting Plastin 3 in WB, ELISA, IP, ICC, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599489
发货至: 中国

Quick Overview for Plastin 3 抗体 (AA 1-580) (ABIN7599489)

抗原

See all Plastin 3 (PLS3) 抗体
Plastin 3 (PLS3)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Plastin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-580

    原理

    Anti-PLS3 Antibody Picoband®

    产品特性

    Anti-PLS3 Antibody Picoband® (ABIN7599489). Tested in WB, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PLS3 recombinant protein (Position: M1-D580). Human PLS3 shares 99% and 97.9% amino acid (aa) sequence identity with mouse and rat PLS3, respectively.
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunoprecipitation, 2-4 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Ackermann, B., Krober, S., Torres-Benito, L., Borgmann, A., Peters, M., Barkooie, S. M. H., Tejero, R., Jakubik, M., Schreml, J., Milbradt, J., Wunderlich, T. F., Riessland, M., Tabares, L., Wirth, B. Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality. Hum. Molec. Genet. 22: 1328-1347, 2013. 2. Lin, C.-S., Aebersold, R. H., Kent, S. B., Varma, M., Leavitt, J. Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts. Molec. Cell. Biol. 8: 4659-4668, 1988. 3. Lin, C.-S., Aebersold, R. H., Leavitt, J. Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain. Molec. Cell. Biol. 10: 1818-1821, 1990.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Plastin 3 (PLS3)

    别名

    PLS3

    背景

    Plastin-3 is a highly conserved protein that in humans is encoded by the PLS3 gene on the X chromosome. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83 % identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

    分子量

    71 kDa

    基因ID

    5358

    UniProt

    P13797
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