RTKN2 抗体 (AA 1-572)
Quick Overview for RTKN2 抗体 (AA 1-572) (ABIN7599487)
抗原
See all RTKN2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-572
-
原理
- Anti-RTKN2 Antibody Picoband®
-
产品特性
- Anti-RTKN2 Antibody Picoband® (ABIN7599487). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human RTKN2 recombinant protein (Position: M1-D572). Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.
-
-
anti-Rhotekin 2 (RTKN2) (AA 1-163) antibody
RTKN2 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Rhotekin 2 (RTKN2) (AA 1-163) antibodyRTKN2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rhotekin 2 (RTKN2) antibodyRTKN2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rhotekin 2 (RTKN2) (AA 1-164) antibodyRTKN2 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Rhotekin 2 (RTKN2) (AA 1-163) antibodyRTKN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Rhotekin 2 (RTKN2) (AA 99-127), (N-Term) antibodyRTKN2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB27444 unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
. Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Collier, F. M., Gregorio-King, C. C., Gough, T. J., Talbot, C. D., Walder, K., Kirkland, M. A. Identification and characterization of a lymphocytic Rho-GTPase effector: rhotekin-2. Biochem. Biophys. Res. Commun. 324: 1360-1369, 2004. 2. Collier, F. M., Loving, A., Baker, A. J., McLeod, J., Walder, K., Kirkland, M. A. RTKN2 induces NF-kappaB dependent resistance to intrinsic apoptosis in HEK cells and regulates BCL-2 genes in human CD4+ lymphocytes. J. Cell Death 2: 9-23, 2009. Note: Electronic Article. 3. Gregorio-King, C. C., Gough, T., Van Der Meer, G. J., Hosking, J. B., Waugh, C. M., McLeod, J. L., Collier, F. M., Kirkland, M. A. Mechanisms of resistance to the cytotoxic effects of oxysterols in human leukemic cells. J. Steroid Biochem. Molec. Biol. 88: 311-320, 2004. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- RTKN2 (Rhotekin 2 (RTKN2))
-
别名
- RTKN2
-
背景
- Rhotekin 2 is a protein in humans that is encoded by the RTKN2 gene. The RTKN2 gene encodes a protein known as Rhotekin-2, which is involved in various cellular processes, including cytoskeletal organization, cell migration, and signal transduction. RTKN2 interacts with Rho GTPases, particularly RhoA, and modulates their activity to regulate actin cytoskeleton dynamics and cell morphology. This protein plays a role in cell adhesion and migration, with implications for tissue development, wound healing, and cancer metastasis. Additionally, RTKN2 has been linked to synaptic plasticity and neuronal development in the brain. Dysregulation of RTKN2 expression or function has been associated with neurological disorders, cardiovascular diseases, and cancer progression. Elucidating the molecular mechanisms underlying RTKN2's diverse functions is crucial for understanding its physiological roles and its potential as a therapeutic target for various diseases.
-
分子量
- 69 kDa
-
基因ID
- 219790
抗原
-
