RTKN2 抗体 (AA 1-572)
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北京 101111
Quick Overview for RTKN2 抗体 (AA 1-572) (ABIN7599487)
抗原
See all RTKN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-572
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原理
- Anti-RTKN2 Antibody
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产品特性
- Anti-RTKN2 Antibody (ABIN7599487). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RTKN2 recombinant protein (Position: M1-D572). Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
. Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RTKN2 (Rhotekin 2 (RTKN2))
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别名
- RTKN2
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背景
- Rhotekin 2 is a protein in humans that is encoded by the RTKN2 gene. The RTKN2 gene encodes a protein known as Rhotekin-2, which is involved in various cellular processes, including cytoskeletal organization, cell migration, and signal transduction. RTKN2 interacts with Rho GTPases, particularly RhoA, and modulates their activity to regulate actin cytoskeleton dynamics and cell morphology. This protein plays a role in cell adhesion and migration, with implications for tissue development, wound healing, and cancer metastasis. Additionally, RTKN2 has been linked to synaptic plasticity and neuronal development in the brain. Dysregulation of RTKN2 expression or function has been associated with neurological disorders, cardiovascular diseases, and cancer progression. Elucidating the molecular mechanisms underlying RTKN2's diverse functions is crucial for understanding its physiological roles and its potential as a therapeutic target for various diseases.
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分子量
- 69 kDa
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基因ID
- 219790
抗原
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