RARS2 抗体 (AA 1-560)
Quick Overview for RARS2 抗体 (AA 1-560) (ABIN7599480)
抗原
See all RARS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-560
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原理
- Anti-RARS2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-RARS2 Antibody Picoband® (ABIN7599480). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RARS2 recombinant protein (Position: M1-R560). Human RARS2 shares 86.1% amino acid (aa) sequence identity with mouse RARS2.
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亚型
- IgG
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anti-Arginyl-tRNA Synthetase 2, Mitochondrial (RARS2) (AA 17-340) antibody
RARS2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginyl-tRNA Synthetase 2, Mitochondrial (RARS2) (AA 369-399), (C-Term) antibodyRARS2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15683 unconjugated
anti-Arginyl-tRNA Synthetase 2, Mitochondrial (RARS2) (AA 17-340) antibodyRARS2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginyl-tRNA Synthetase 2, Mitochondrial (RARS2) (AA 1-578) antibodyRARS2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Arginyl-tRNA Synthetase 2, Mitochondrial (RARS2) (AA 230-578) antibodyRARS2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginyl-tRNA Synthetase 2, Mitochondrial (RARS2) antibodyRARS2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Edvardson, S., Shaag, A., Kolesnikova, O., Gomori, J. M., Tarassov, I., Einbinder, T., Saada, E., Elpeleg, O. Deleterious mutation in the mitochondrial arginyl-transfer RNA synthetase gene is associated with pontocerebellar hypoplasia. Am. J. Hum. Genet. 81: 857-862, 2007. 2. Li, Z., Schonberg, R., Guidugli, L., Johnson, A. K., Arnovitz, S., Yang, S., Scafidi, J., Summar, M. L., Vezina, G., Das, S., Chapman, K., del Gaudio, D. A novel mutation in the promoter of RARS2 causes pontocerebellar hypoplasia in two siblings. J. Hum. Genet. 60: 363-369, 2015. 3. Rankin, J., Brown, R., Dobyns, W. B., Harington, J., Patel, J., Quinn, M., Brown, G. Pontocerebellar hypoplasia type 6: a British case with PEHO-like features. Am. J. Med. Genet. 152A: 2079-2084, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RARS2 (Arginyl-tRNA Synthetase 2, Mitochondrial (RARS2))
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别名
- RARS2
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背景
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Synonyms: RARS2, RARSL, Probable arginine--tRNA ligase, mitochondrial, EC 6.1.1.19, Arginyl-tRNA synthetase, ArgRS
Background: This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants.
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分子量
- 66 kDa
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基因ID
- 57038
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UniProt
- Q5T160
抗原
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