RUFY4 抗体 (AA 1-553)
Quick Overview for RUFY4 抗体 (AA 1-553) (ABIN7599475)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-553
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原理
- Anti-RUFY4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RUFY4 Antibody Picoband® (ABIN7599475). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RUFY4 recombinant protein (Position: M1-K553).
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亚型
- IgG
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anti-RUN and FYVE Domain Containing 4 (RUFY4) (AA 174-473) antibody
RUFY4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RUN and FYVE Domain Containing 4 (RUFY4) (AA 1-398) antibodyRUFY4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RUN and FYVE Domain Containing 4 (RUFY4) (C-Term) antibodyRUFY4 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Terawaki, S. , Camosseto, V. , Prete, F. , Wenger, T. , Papadopoulos, A. , & Rondeau, C. , et al. (2015). Run and fyve domain-containing protein 4 enhances autophagy and lysosome tethering in response to interleukin-4. The Journal of Cell Biology, 210(7), 1133-1152. 2. Chen, S. , Robert, F. , Lambertus, K. , Yuan, L. , Wang, J. , & Kathryn, R. , et al. (2018). An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. Nature Genetics. 3. Haenig, C. , Atias, N. , Taylor, A. K. , Mazza, A. , & Wanker, E. E. . (2020). Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains. Cell Reports, 32(7), 108050. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RUFY4 (RUN and FYVE Domain Containing 4 (RUFY4))
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别名
- RUFY4
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背景
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Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: Enables phosphatidylinositol-3-phosphate binding activity. Involved in autophagosome assembly, cellular response to interleukin-4, and positive regulation of macroautophagy. Located in autophagosome.
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分子量
- 64 kDa
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基因ID
- 285180
抗原
-
