KLC1 抗体 (AA 1-537)
Quick Overview for KLC1 抗体 (AA 1-537) (ABIN7599468)
抗原
See all KLC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-537
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原理
- Anti-KLC1 Antibody Picoband® (monoclonal, 4F2D7)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-KLC1 Antibody Picoband® (monoclonal, 4F2D7) (ABIN7599468). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KLC1 recombinant protein (Position: M1-D537).
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亚型
- IgG2b
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anti-Kinesin Light Chain 1 (KLC1) (AA 1-254) antibody
KLC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Light Chain 1 (KLC1) antibodyKLC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Light Chain 1 (KLC1) (AA 389-415) antibodyKLC1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22636 unconjugated
anti-Kinesin Light Chain 1 (KLC1) (AA 274-573) antibodyKLC1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Light Chain 1 (KLC1) (AA 1-100) antibodyKLC1 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Light Chain 1 (KLC1) (AA 1-560) antibodyKLC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kinesin Light Chain 1 (KLC1) (AA 261-560) antibodyKLC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Light Chain 1 (KLC1) antibodyKLC1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Bracale, A., Cesca, F., Neubrand, V. E., Newsome, T. P., Way, M., Schiavo, G. Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation. Molec. Biol. Cell 18: 142-152, 2007. 2. Cabeza-Arvelaiz, Y., Shih, L.-C. N., Hardman, N., Asselbergs, F., Bilbe, G., Schmitz, A., White, B., Siciliano, M. J., Lachman, L. B. Cloning and genetic organization of the human kinesin light-chain (KLC) gene. DNA Cell Biol. 12: 881-892, 1993. 3. Chernajovsky, Y., Brown, A., Clark, J. Human kinesin light (beta) chain gene: DNA sequence and functional characterization of its promoter and first exon. DNA Cell Biol. 15: 965-974, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- KLC1 (Kinesin Light Chain 1 (KLC1))
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别名
- KLC1
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背景
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Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115
Background: Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.
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分子量
- 65 kDa
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基因ID
- 3831
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UniProt
- Q07866
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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