NCF2 抗体 (AA 1-526)
Quick Overview for NCF2 抗体 (AA 1-526) (ABIN7599462)
抗原
See all NCF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-526
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原理
- Anti-NOXA2/p67phox/NCF2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NOXA2/p67phox/NCF2 Antibody Picoband® (ABIN7599462). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NOXA2/p67phox/NCF2 recombinant protein (Position: M1-V526).
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亚型
- IgG
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anti-Neutrophil Cytosolic Factor 2 (NCF2) (AA 178-526) antibody
NCF2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 2 (NCF2) (N-Term) antibodyNCF2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 2 (NCF2) (AA 227-526) antibodyNCF2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 2 (NCF2) (AA 355-526) antibodyNCF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 2 (NCF2) (AA 354-525) antibodyNCF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 2 (NCF2) (AA 1-526) antibodyNCF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 2 (NCF2) antibodyNCF2 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 2 (NCF2) (AA 429-478) antibodyNCF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Francke, U., Hsieh, C.-L., Foellmer, B. E., Lomax, K. J., Malech, H. L., Leto, T. L. Genes for two autosomal recessive forms of chronic granulomatous disease assigned to 1q25 (NCF2) and 7q11.23 (NCF1). Am. J. Hum. Genet. 47: 483-492, 1990. 2. Noack, D., Rae, J., Cross, A. R., Munoz, J., Salmen, S., Mendoza, J. A., Rossi, N., Curnutte, J. T., Heyworth, P. G. Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase. Hum. Genet. 105: 460-467, 1999. 3. Sancho-Shimizu, V., Malo, D. Sequencing, expression, and functional analyses support the candidacy of Ncf2 in susceptibility to Salmonella Typhimurium infection in wild-derived mice. J. Immun. 176: 6954-6961, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))
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别名
- NCF2
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背景
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Synonyms: Syntenin-1, Melanoma differentiation-associated protein 9, MDA-9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, TACIP18, Scaffold protein Pbp1, Syndecan-binding protein 1, SDCBP, MDA9, SYCL
Tissue Specificity: Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma. Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.
Background: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 60 kDa
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基因ID
- 4688
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UniProt
- P19878
抗原
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