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TRMT2B 抗体 (AA 1-504)

This anti-TRMT2B antibody is a 兔 多克隆 antibody detecting TRMT2B in WB, IHC, ELISA, FACS 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599456
发货至: 中国

Quick Overview for TRMT2B 抗体 (AA 1-504) (ABIN7599456)

抗原

See all TRMT2B 抗体
TRMT2B (tRNA Methyltransferase 2 Homolog B (TRMT2B))

适用

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人, 小鼠, 大鼠

宿主

  • 16
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克隆类型

  • 18
多克隆

标记

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This TRMT2B antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-504

    原理

    Anti-TRMT2B Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TRMT2B Antibody Picoband® (ABIN7599456). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TRMT2B recombinant protein (Position: M1-R504).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Minczuk, M. , & Powell, C. A. . Trmt2b is responsible for both trna and rrna m5u-methylation in human mitochondria. 2. Dai, W. , Li, A. , Yu, N. J. , Nguyen, T. , Leach, R. W. , & M Wühr, et al. Activity-based rna-modifying enzyme probing reveals dus3l-mediated dihydrouridylation. Nature chemical biology. 3. Daakour, S. , Hajingabo, L. J. , Kerselidou, D. , Devresse, A. , Kettmann, R. , & Simonis, N. , et al. (2016). Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals ext-1 tumor suppressor as a notch1 and fbwx7 common interactor. BMC Cancer.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TRMT2B (tRNA Methyltransferase 2 Homolog B (TRMT2B))

    别名

    TRMT2B

    背景

    Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.

    分子量

    47 kDa

    基因ID

    79979
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