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TRMT2B 抗体 (AA 1-504)

TRMT2B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599456
发货至: 中国
  • 抗原 See all TRMT2B 抗体
    TRMT2B (tRNA Methyltransferase 2 Homolog B (TRMT2B))
    抗原表位
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-504
    适用
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 16
    • 2
    克隆类型
    • 18
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRMT2B antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
    原理
    Anti-TRMT2B Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-TRMT2B Antibody Picoband® (ABIN7599456). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human TRMT2B recombinant protein (Position: M1-R504).
    亚型
    IgG
    Top Product
    Discover our top product TRMT2B Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Minczuk, M. , & Powell, C. A. . Trmt2b is responsible for both trna and rrna m5u-methylation in human mitochondria. 2. Dai, W. , Li, A. , Yu, N. J. , Nguyen, T. , Leach, R. W. , & M Wühr, et al. Activity-based rna-modifying enzyme probing reveals dus3l-mediated dihydrouridylation. Nature chemical biology. 3. Daakour, S. , Hajingabo, L. J. , Kerselidou, D. , Devresse, A. , Kettmann, R. , & Simonis, N. , et al. (2016). Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals ext-1 tumor suppressor as a notch1 and fbwx7 common interactor. BMC Cancer.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    TRMT2B (tRNA Methyltransferase 2 Homolog B (TRMT2B))
    别名
    TRMT2B (TRMT2B 产品)
    背景

    Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.

    分子量
    47 kDa
    基因ID
    79979
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