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PTBP2 抗体 (AA 1-504)

This anti-PTBP2 antibody is a 兔 多克隆 antibody detecting PTBP2 in WB, ELISA, IHC, IF, ICC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599452
发货至: 中国

Quick Overview for PTBP2 抗体 (AA 1-504) (ABIN7599452)

抗原

See all PTBP2 抗体
PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

适用

  • 27
  • 11
  • 10
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 20
  • 6
  • 1

克隆类型

  • 19
  • 8
多克隆

标记

  • 23
  • 2
  • 1
  • 1
This PTBP2 antibody is un-conjugated

应用范围

  • 23
  • 11
  • 9
  • 7
  • 5
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-504

    原理

    Anti-PTBP2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PTBP2 Antibody Picoband® (ABIN7599452). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PTBP2 recombinant protein (Position: M1-A504).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Makeyev, E. V., Zhang, J., Carrasco, M. A., Maniatis, T. The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Molec. Cell 27: 435-448, 2007. 2. Rahman, L., Bliskovski, V., Kaye, F. J., Zajac-Kaye, M. Evolutionary conservation of a 2-kb intronic sequence flanking a tissue-specific alternative exon in the PTBP2 gene. Genomics 83: 76-84, 2004.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

    别名

    PTBP2

    背景

    Synonyms: Polypyrimidine tract-binding protein 2, Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB, PTB-like protein, PTBP2, NPTB, PTB, PTBLP

    Tissue Specificity: Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non-neuronal tissues.

    Background: Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene. It is mapped to 1p21.3. The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants.

    分子量

    57 kDa

    基因ID

    58155

    途径

    Ribonucleoprotein Complex Subunit Organization, SARS-CoV-2 Protein Interactome
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