MSL3 抗体 (AA 1-498)
Quick Overview for MSL3 抗体 (AA 1-498) (ABIN7599447)
抗原
See all MSL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-498
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原理
- Anti-MSL3 Antibody Picoband®
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产品特性
- Anti-MSL3 Antibody Picoband® (ABIN7599447). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SLC7A7 recombinant protein (Position: M1-D498). Human SLC7A7 shares 90.8% and 91.6% amino acid (aa) sequence identity with mouse and rat SLC7A7, respectively.
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anti-Male-Specific Lethal 3 Homolog (MSL3) (AA 1-521) antibody
MSL3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Male-Specific Lethal 3 Homolog (MSL3) (Center) antibodyMSL3 适用: 人, 小鼠 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Male-Specific Lethal 3 Homolog (MSL3) (C-Term) antibodyMSL3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Pig, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Male-Specific Lethal 3 Homolog (MSL3) (AA 287-336) antibodyMSL3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Male-Specific Lethal 3 Homolog (MSL3) (N-Term) antibodyMSL3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Basilicata, M. F., Bruel, A.-L., Semplicio, G., Valsecchi, C. I. K., Aktas, T., Duffourd, Y., Rumpf, T., Morton, J., Bache, I., Szymanski, W. G., Gilissen, C., Vanakker, O., and 29 others. De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nature Genet. 50: 1442-1451, 2018. 2. Brunet, T., McWalter, K., Mayerhanser, K., Anbouba, G. M., Armstrong-Javors, A., Bader, I., Baugh, E., Begtrup, A., Bupp, C. P., Callewaert, B. L., Cereda, A., Cousin, M. A., and 49 others. Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder. Genet. Med. 23: 384-395, 2021. 3. Prakash, S. K., Van den Veyver, I. B., Franco, B., Volta, M., Ballabio, A., Zoghbi, H. Y. Characterization of a novel chromo domain gene in Xp22.3 with homology to Drosophila msl-3. Genomics 59: 77-84, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MSL3 (Male-Specific Lethal 3 Homolog (MSL3))
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别名
- MSL3
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背景
- Y+L amino acid transporter 1 is a protein that in humans is encoded by the SLC7A7 gene. The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.
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分子量
- 70 kDa
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基因ID
- 10943
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UniProt
- Q8N5Y2
抗原
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