NPLOC4 抗体 (AA 1-495)
Quick Overview for NPLOC4 抗体 (AA 1-495) (ABIN7599442)
抗原
See all NPLOC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-495
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原理
- Anti-NPL4/NPLOC4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NPL4/NPLOC4 Antibody Picoband® (ABIN7599442). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NPL4/NPLOC4 recombinant protein (Position: M1-N495).
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亚型
- IgG
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anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 1-270) antibody
NPLOC4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 1-608) antibodyNPLOC4 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 1-608) antibodyNPLOC4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Protein Localization 4 Homolog (NPLOC4) (AA 96-145) antibodyNPLOC4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Botta, A., Tandoi, C., Fini, G., Calabrese, G., Dallapiccola, B., Novelli, G. Cloning and characterization of the gene encoding human NPL4, a protein interacting with the ubiquitin fusion-degradation protein (UFD1L). Gene 275: 39-46, 2001. 2. Nagase, T., Kikuno, R., Ishikawa, K., Hirosawa, M., Ohara, O. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 143-150, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
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别名
- NPLOC4
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背景
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Synonyms: Serine/threonine-protein kinase LMTK3, Lemur tyrosine kinase 3, LMTK3, KIAA1883, TYKLM3
Background: Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene. Nuclear protein localization protein 4 (NPL4, NPLOC4) was originally identified as a yeast nuclear transport protein that was later recognized as a critical component of the endoplasmic reticulum-associated degradation (ERAD) pathway. Mammalian NPL4 protein has an amino-terminal ubiquitin-like domain containing a p97 binding site, and a conserved carboxy-terminal zinc finger (NZF) motif responsible for binding ubiquitinated target proteins. NPL4 binds ubiquitin fusion degradation protein 1 (UFD1) to form a heterodimer that associates with the p97 AAA-ATPase, creating a protein complex that mediates delivery of ubiquitinated ER proteins to the proteasome.
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分子量
- 72 kDa
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基因ID
- 55666
抗原
-
