MARCO 抗体 (AA 1-489)
Quick Overview for MARCO 抗体 (AA 1-489) (ABIN7599438)
抗原
See all MARCO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-489
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原理
- Anti-MARCO Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-MARCO Antibody Picoband® (ABIN7599438). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MARCO recombinant protein (Position: M1-R489). Human MARCO shares 66.5% amino acid (aa) sequence identity with mouse MARCO.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Arredouani, M., Yang, Z., Ning, Y. Y., Qin, G., Soininen, R., Tryggvason, K., Kobzik, L. The scavenger receptor MARCO is required for lung defense against Pneumococcal pneumonia and inhaled particles. J. Exp. Med. 200: 267-272, 2004. 2. Dorrington, M. G., Roche, A. M., Chauvin, S. E., Tu, Z., Mossman, K. L., Weiser, J. N., Bowdish, D. M. E. MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx. J. Immun. 190: 250-258, 2013. 3. Elomaa, O., Kangas, M., Sahlberg, C., Tuukkanen, J., Sormunen, R., Liakka, A., Thesleff, I., Kraal, G., Tryggvason, K. Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell 80: 603-609, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
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别名
- MARCO
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背景
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Synonyms: MARCO, SCARA2, Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2
Background: Macrophage receptor with collagenous structure (MARCO) is a protein that in humans is encoded by the MARCO gene.
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分子量
- 53 kDa
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途径
- Activation of Innate immune Response
抗原
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