HMGCS2 抗体 (AA 1-487)
Quick Overview for HMGCS2 抗体 (AA 1-487) (ABIN7599435)
抗原
See all HMGCS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-487
-
原理
- Anti-HMGCS2 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-HMGCS2 Antibody Picoband® (ABIN7599435). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human HMGCS2 recombinant protein (Position: M1-P487).
-
亚型
- IgG
-
-
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) (AA 1-167) antibody
HMGCS2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) antibodyHMGCS2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) (AA 269-508) antibodyHMGCS2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) (AA 426-508) antibodyHMGCS2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) antibodyHMGCS2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) (AA 424-508) antibodyHMGCS2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) (AA 478-508), (C-Term) antibodyHMGCS2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19373 unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) (N-Term) antibodyHMGCS2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 山羊, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) antibodyHMGCS2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) (AA 478-508) antibodyHMGCS2 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aledo, R., Zschocke, J., Pie, J., Mir, C., Fiesel, S., Mayatepek, E., Hoffmann, G. F., Casals, N., Hegardt, F. G. Genetic basis of mitochondrial HMG-CoA synthase deficiency. Hum. Genet. 109: 19-23, 2001. 2. Ayte, J., Gil-Gomez, G., Haro, D., Marrero, P. F., Hegardt, F. G. Rat mitochondrial and cytosolic 3-hydroxy-3-methylglutaryl-CoA synthases are encoded by two different genes. Proc. Nat. Acad. Sci. 87: 3874-3878, 1990. 3. Bouchard, L., Robert, M.-F., Vinarov, D., Stanley, C. A., Thompson, G. N., Morris, A., Leonard, J. V., Quant, P., Hsu, B. Y. L., Boneh, A., Boukaftane, Y., Ashmarina, L., Wang, S., Miziorko, H., Mitchell, G. A. Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: clinical course and description of causal mutations in two patients. Pediat. Res. 49: 326-331, 2001. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
-
别名
- HMGCS2
-
背景
-
Synonyms: Urokinase-type plasminogen activator, U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B, PLAU
Tissue Specificity: Expressed in the prostate gland and prostate cancers.
Background: 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) is an enzyme in humans that is encoded by the HMGCS2 gene. The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
分子量
- 50 kDa
-
基因ID
- 3158
-
UniProt
- P54868
-
途径
- Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha
抗原
-
