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GSDMD 抗体 (AA 1-484)

The 小鼠 单克隆 anti-GSDMD antibody (Clone 3D5) (ABIN7599432) specifically detects GSDMD in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7599432
发货至: 中国
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Quick Overview for GSDMD 抗体 (AA 1-484) (ABIN7599432)

抗原

See all GSDMD 抗体
GSDMD (Gasdermin D (GSDMD))

适用

  • 31
  • 5
  • 3

宿主

  • 24
  • 10
  • 1
小鼠

克隆类型

  • 23
  • 12
单克隆

标记

  • 28
  • 3
  • 1
  • 1
  • 1
  • 1
This GSDMD antibody is un-conjugated

应用范围

  • 28
  • 13
  • 11
  • 11
  • 7
  • 7
  • 5
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

3D5
  • 抗原表位

    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-484

    原理

    Anti-GSDMD Antibody (monoclonal, 3D5)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-GSDMD Antibody (monoclonal, 3D5) (ABIN7599432). Tested in IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GSDMD recombinant protein (Position: M1-H484).

    亚型

    IgG2a
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    GSDMD (Gasdermin D (GSDMD))

    别名

    GSDMD

    背景

    Synonyms: "chromosomal protein, Nonhistone, HMG4 antibody|High mobility group (nonhistone chromosomal) protein 4 antibody|High mobility group box 3 antibody|High mobility group protein 2a antibody|High mobility group protein 4 antibody|High mobility group protein B3 antibody| High mobility group protein HMG4 antibody|HMG 4 antibody|HMG-2a antibody|HMG-4 antibody|HMG2A antibody|HMGB 3 antibody|HMGB3 antibody| HMGB3_HUMAN antibody|MGC90319 antibody|Non histone chromosomal protein antibody|Nonhistone chromosomal protein HMG4 antibody"

    Tissue Specificity: Expressed predominantly in placenta.

    Background: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

    分子量

    53 kDa

    基因ID

    79792

    UniProt

    P57764

    途径

    Inflammasome
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