GSDMD 抗体 (AA 1-484)
Quick Overview for GSDMD 抗体 (AA 1-484) (ABIN7599431)
抗原
See all GSDMD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-484
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原理
- Anti-GSDMD Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GSDMD Antibody Picoband® (ABIN7599431). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GSDMD recombinant protein (Position: M1-H484).
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亚型
- IgG
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anti-Gasdermin D (GSDMD) (AA 1-484) antibody
GSDMD 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B2 unconjugated
anti-Gasdermin D (GSDMD) (AA 276-484) antibodyGSDMD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-485) antibodyGSDMD 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B2 unconjugated
anti-Gasdermin D (GSDMD) antibodyGSDMD 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) antibodyGSDMD 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-326) antibodyGSDMD 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-256) antibodyGSDMD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 232-484) antibodyGSDMD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-484) antibodyGSDMD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-484) antibodyGSDMD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ruhl, S., Shkarina, K., Demarco, B., Heilig, R., Santos, J. C., Broz, P. ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation. Science 362: 956-960, 2018. 2. Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., Zhuang, Y., Cai, T., Wang, F., Shao, F. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526: 660-665, 2015. 3. Zhu, Q., Zheng, M., Balakrishnan, A., Karki, R., Kanneganti, T.-D. Gasdermin D promotes AIM2 inflammasome activation and is required for host protection against Francisella novicida. J. Immun. 201: 3662-3668, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GSDMD (Gasdermin D (GSDMD))
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别名
- GSDMD
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背景
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Synonyms: gasdermin D, gasdermin-D
Tissue Specificity: Brain, placental, and gut tissues.
Background: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
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分子量
- 30, 53 kDa
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基因ID
- 79792
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UniProt
- P57764
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途径
- Inflammasome
抗原
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