RORB 抗体 (AA 1-470)
Quick Overview for RORB 抗体 (AA 1-470) (ABIN7599423)
抗原
See all RORB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-470
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原理
- Anti-ROR beta/RORB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ROR beta/RORB Antibody Picoband® (ABIN7599423). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ROR beta/RORB recombinant protein (Position: M1-K470).
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亚型
- IgG
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anti-RAR-Related Orphan Receptor B (RORB) (AA 136-224) antibody
RORB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (Hinge Region) antibodyRORB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 绵羊, 兔, 小鸡, 猴, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (Hinge Region) antibodyRORB 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (Ligand Binding Domain) antibodyRORB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 绵羊, 兔, 小鸡, 猴, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor B (RORB) antibodyMicroarray verified RORB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB572874 unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (AA 329-358), (C-Term) antibodyRORB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34135 unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (C-Term) antibodyRORB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 绵羊, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (AA 385-470) antibodyRORB 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (AA 1-269) antibodyRORB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor B (RORB) (AA 86-135) antibodyRORB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 绵羊, 兔, 豚鼠, 斑马鱼, 小鸡, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Andre, E., Conquet, F., Steinmayr, M., Stratton, S. C., Porciatti, V., Becker-Andre, M. Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice. EMBO J. 17: 3867-3877, 1998. 2. Baler, R., Coon, S., Klein, D. C. Orphan nuclear receptor RZR-beta: cyclic AMP regulates expression in the pineal gland. Biochem. Biophys. Res. Commun. 220: 975-978, 1996. 3. Carlberg, C., Hooft van Huijsduijnen, R., Staple, J. K., DeLamarter, J. F., Becker-Andre, M. RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers. Molec. Endocr. 8: 757-770, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RORB (RAR-Related Orphan Receptor B (RORB))
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别名
- RORB
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背景
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Synonyms: One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B
Tissue Specificity: Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.
Background: RAR-related orphan receptor beta (ROR-beta), also known as NR1F2 (nuclear receptor subfamily 1, group F, member 2) is a nuclear receptor that in humans is encoded by the RORB gene. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm.
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分子量
- 53 kDa
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基因ID
- 6096
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UniProt
- Q92753
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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