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SHMT1 抗体 (AA 1-470)

This anti-SHMT1 antibody is a 小鼠 单克隆 antibody detecting SHMT1 in WB, IHC, IF, ICC 和 FACS. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7599420
发货至: 中国

Quick Overview for SHMT1 抗体 (AA 1-470) (ABIN7599420)

抗原

See all SHMT1 抗体
SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 39
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小鼠

克隆类型

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单克隆

标记

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This SHMT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

9C7
  • 抗原表位

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    AA 1-470

    原理

    Anti-SHMT1 Antibody Picoband® (monoclonal, 9C7)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SHMT1 Antibody Picoband® (monoclonal, 9C7) (ABIN7599420). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SHMT1 recombinant protein (Position: M1-S470).

    亚型

    IgG1
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Monkey, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Byrne, P. C., Shipley, J. M., Chave, K. J., Sanders, P. G., Snell, K. Characterisation of a human serine hydroxymethyltransferase pseudogene and its localisation of 1p32.3-33. Hum. Genet. 97: 340-344, 1996. 2. Elsea, S. H., Juyal, R. C., Jiralerspong, S., Finucane, B. M., Pandolfo, M., Greenberg, F., Baldini, A., Stover, P., Patel, P. I. Haploinsufficiency of cytosolic serine hydroxymethyltransferase in the Smith-Magenis syndrome. Am. J. Hum. Genet. 57: 1342-1350, 1995. 3. Garrow, T. A., Brenner, A. A., Whitehead, V. M., Chen, X.-N., Duncan, R. G., Korenberg, J. R., Shane, B. Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization. J. Biol. Chem. 268: 11910-11916, 1993.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

    别名

    SHMT1

    背景

    Synonyms: "chromosomal protein, Nonhistone, HMG4 antibody|High mobility group (nonhistone chromosomal) protein 4 antibody|High mobility group box 3 antibody|High mobility group protein 2a antibody|High mobility group protein 4 antibody|High mobility group protein B3 antibody| High mobility group protein HMG4 antibody|HMG 4 antibody|HMG-2a antibody|HMG-4 antibody|HMG2A antibody|HMGB 3 antibody|HMGB3 antibody| HMGB3_HUMAN antibody|MGC90319 antibody|Non histone chromosomal protein antibody|Nonhistone chromosomal protein HMG4 antibody"

    Tissue Specificity: Expressed predominantly in placenta.

    Background: This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.

    分子量

    53 kDa

    基因ID

    6470

    UniProt

    P34896
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