RUFY3 抗体 (AA 1-469)
Quick Overview for RUFY3 抗体 (AA 1-469) (ABIN7599418)
抗原
See all RUFY3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-469
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原理
- Anti-RUFY3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RUFY3 Antibody Picoband® (ABIN7599418). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RUFY3 recombinant protein (Position: M1-H469).
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亚型
- IgG
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anti-RUN and FYVE Domain Containing 3 (RUFY3) (AA 243-352) antibody
RUFY3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RUN and FYVE Domain Containing 3 (RUFY3) (AA 1-469) antibodyRUFY3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RUN and FYVE Domain Containing 3 (RUFY3) antibodyRUFY3 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-RUN and FYVE Domain Containing 3 (RUFY3) (C-Term) antibodyRUFY3 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, Pig, 兔, 非洲爪蟾, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RUN and FYVE Domain Containing 3 (RUFY3) (AA 1-65) antibodyRUFY3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RUN and FYVE Domain Containing 3 (RUFY3) (C-Term) antibodyRUFY3 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hertz, N. T., Adams, E. L., Weber, R. A., Shen, R. J., O'Rourke, M. K., Simon, D. J., Zebroski, H., Olsen, O., Morgan, C. W., Mileur, T. R., Hitchcock, A. M., Sinnott Armstrong, N. A., Wainberg, M., Bassik, M. C., Molina, H., Wells, J. A., Tessier-Lavigne, M. Neuronally enriched RUFY3 is required for caspase-mediated axon degeneration. Neuron 103: 412-422, 2019. 2. Mori, T., Wada, T., Suzuki, T., Kubota, Y., Inagaki, N. Singar1, a novel RUN domain-containing protein, suppresses formation of surplus axons for neuronal polarity. J. Biol. Chem. 282: 19884-19893, 2007. 3. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 5: 355-364, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))
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别名
- RUFY3
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背景
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Synonyms: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFP, MED20, TRFP,
Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.
Background: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.
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分子量
- 53-65 kDa
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基因ID
- 22902
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UniProt
- Q7L099
抗原
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