Macrophage Scavenger Receptor 1 抗体 (AA 1-451)
Quick Overview for Macrophage Scavenger Receptor 1 抗体 (AA 1-451) (ABIN7599407)
抗原
See all Macrophage Scavenger Receptor 1 (MSR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-451
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原理
- Anti-CD204/Msr1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-/Msr1 Antibody Picoband® (ABIN7599407). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse CD204/Msr1 recombinant protein (Position: M1-D451).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 9/30/2015. 2. Hemmasi, S., Czulkies, B. A., Schorch, B., Veit, A., Aktories, K., Papatheodorou, P. Interaction of the Clostridium difficile binary toxin CDT and its host cell receptor, lipolysis-stimulated lipoprotein receptor (LSR). J. Biol. Chem. 290: 14031-14044, 2015. 3. Maddirevula, S., Alhebbi, H., Alqahtani, A., Algoufi, T., Alsaif, H. S., Ibrahim, N., Abdulwahab, F., Barr, M., Alzaidan, H., Almehaideb, A., AlSasi, O., Alhashem, A., Al-Hussaini, H., Wali, S., Alkuraya, F. S. Identification of novel loci for pediatric cholestatic liver disease defined by KIF12, PPM1F, USP53, LSR, and WDR83OS pathogenic variants. Genet. Med. 21: 1164-1172, 2019. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Macrophage Scavenger Receptor 1 (MSR1)
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别名
- Msr1
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背景
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Synonyms: Acid-sensing ion channel 1, ASIC1,Amiloride-sensitive cation channel 2, neuronal, Brain sodium channel 2, BNaC2, ASIC1, ACCN2, BNAC2
Tissue Specificity: Expressed in most or all neurons.
Background: Macrophage scavenger receptor 1, also known as MSR1, is a protein which in humans is encoded by the MSR1 gene. Enables amyloid-beta binding activity, cargo receptor activity, and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis, positive regulation of cholesterol storage, and positive regulation of macrophage derived foam cell differentiation. Acts upstream of or within lipoprotein transport. Located in plasma membrane. Is expressed in several structures, including alimentary system, limb, neural tube, reproductive system, and yolk sac. Human ortholog(s) of this gene implicated in Barrett's esophagus, arteriosclerosis, and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1).
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分子量
- 75-90 kDa
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基因ID
- 20288
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UniProt
- P30204
抗原
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