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Macrophage Scavenger Receptor 1 抗体 (AA 1-451)

This anti-Macrophage Scavenger Receptor 1 antibody is a 兔 多克隆 antibody detecting Macrophage Scavenger Receptor 1 in WB, ELISA 和 FACS. Suitable for 小鼠.
产品编号 ABIN7599407
发货至: 中国

Quick Overview for Macrophage Scavenger Receptor 1 抗体 (AA 1-451) (ABIN7599407)

抗原

See all Macrophage Scavenger Receptor 1 (MSR1) 抗体
Macrophage Scavenger Receptor 1 (MSR1)

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Macrophage Scavenger Receptor 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
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    AA 1-451

    原理

    Anti-CD204/Msr1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-/Msr1 Antibody Picoband® (ABIN7599407). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse CD204/Msr1 recombinant protein (Position: M1-D451).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Gross, M. B. Personal Communication. Baltimore, Md. 9/30/2015. 2. Hemmasi, S., Czulkies, B. A., Schorch, B., Veit, A., Aktories, K., Papatheodorou, P. Interaction of the Clostridium difficile binary toxin CDT and its host cell receptor, lipolysis-stimulated lipoprotein receptor (LSR). J. Biol. Chem. 290: 14031-14044, 2015. 3. Maddirevula, S., Alhebbi, H., Alqahtani, A., Algoufi, T., Alsaif, H. S., Ibrahim, N., Abdulwahab, F., Barr, M., Alzaidan, H., Almehaideb, A., AlSasi, O., Alhashem, A., Al-Hussaini, H., Wali, S., Alkuraya, F. S. Identification of novel loci for pediatric cholestatic liver disease defined by KIF12, PPM1F, USP53, LSR, and WDR83OS pathogenic variants. Genet. Med. 21: 1164-1172, 2019.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Macrophage Scavenger Receptor 1 (MSR1)

    别名

    Msr1

    背景

    Synonyms: Acid-sensing ion channel 1, ASIC1,Amiloride-sensitive cation channel 2, neuronal, Brain sodium channel 2, BNaC2, ASIC1, ACCN2, BNAC2

    Tissue Specificity: Expressed in most or all neurons.

    Background: Macrophage scavenger receptor 1, also known as MSR1, is a protein which in humans is encoded by the MSR1 gene. Enables amyloid-beta binding activity, cargo receptor activity, and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis, positive regulation of cholesterol storage, and positive regulation of macrophage derived foam cell differentiation. Acts upstream of or within lipoprotein transport. Located in plasma membrane. Is expressed in several structures, including alimentary system, limb, neural tube, reproductive system, and yolk sac. Human ortholog(s) of this gene implicated in Barrett's esophagus, arteriosclerosis, and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1).

    分子量

    75-90 kDa

    基因ID

    20288

    UniProt

    P30204
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