TXNDC3/NME8 抗体 (AA 1-446)
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- 抗原 See all TXNDC3/NME8 (TXNDC3) 抗体
- TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))
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抗原表位
- AA 1-446
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TXNDC3/NME8 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- Anti-TXNDC3/NME8 Antibody Picoband®
- 交叉反应 (详细)
- No cross-reactivity with other proteins
- 产品特性
- Anti-TXNDC3-NME8 Antibody Picoband® (ABIN7599402). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human TXNDC3/NME8 recombinant protein (Position: M1-H446). Human TXNDC3/NME8 shares 63% and 61.2% amino acid (aa) sequence identity with mouse and rat TXNDC3/NME8, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product TXNDC3 Primary Antibody
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Duriez, B., Duquesnoy, P., Escudier, E., Bridoux, A.-M., Escalier, D., Rayet, I., Marcos, E., Vojtek, A.-M., Bercher, J.-F., Amselem, S. A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia. Proc. Nat. Acad. Sci. 104: 3336-3341, 2007. Note: Erratum: Proc. Nat. Acad. Sci. 104: 6490 only, 2007. 2. Sadek, C. M., Damdimopoulos, A. E., Pelto-Huikko, M., Gustafsson, J.-A., Spyrou, G., Miranda-Vizuete, A. Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells. Genes Cells 6: 1077-1090, 2001. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))
- 别名
- NME8 (TXNDC3 产品)
- 背景
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Synonyms: NME8, SPTRX2, TXNDC3, Thioredoxin domain-containing protein 3, NM23-H8, NME/NM23 family member 8, Spermatid-specific thioredoxin-2, Sptrx-2
Background: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
- 分子量
- 67 kDa
- 基因ID
- 51314
- UniProt
- Q8N427
- 途径
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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