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TXNDC3/NME8 抗体 (AA 1-446)

This anti-TXNDC3/NME8 antibody is a 兔 多克隆 antibody detecting TXNDC3/NME8 in ELISA, WB 和 FACS. Suitable for 人 和 大鼠.
产品编号 ABIN7599402
发货至: 中国

Quick Overview for TXNDC3/NME8 抗体 (AA 1-446) (ABIN7599402)

抗原

See all TXNDC3/NME8 (TXNDC3) 抗体
TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

适用

  • 21
  • 2
  • 2
人, 大鼠

宿主

  • 16
  • 4
  • 1

克隆类型

  • 19
  • 2
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
This TXNDC3/NME8 antibody is un-conjugated

应用范围

  • 12
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-446

    原理

    Anti-TXNDC3/NME8 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-TXNDC3-NME8 Antibody Picoband® (ABIN7599402). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TXNDC3/NME8 recombinant protein (Position: M1-H446). Human TXNDC3/NME8 shares 63% and 61.2% amino acid (aa) sequence identity with mouse and rat TXNDC3/NME8, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL
    1. Duriez, B., Duquesnoy, P., Escudier, E., Bridoux, A.-M., Escalier, D., Rayet, I., Marcos, E., Vojtek, A.-M., Bercher, J.-F., Amselem, S. A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia. Proc. Nat. Acad. Sci. 104: 3336-3341, 2007. Note: Erratum: Proc. Nat. Acad. Sci. 104: 6490 only, 2007. 2. Sadek, C. M., Damdimopoulos, A. E., Pelto-Huikko, M., Gustafsson, J.-A., Spyrou, G., Miranda-Vizuete, A. Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells. Genes Cells 6: 1077-1090, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))

    别名

    NME8

    背景

    Synonyms: NME8, SPTRX2, TXNDC3, Thioredoxin domain-containing protein 3, NM23-H8, NME/NM23 family member 8, Spermatid-specific thioredoxin-2, Sptrx-2

    Background: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.

    分子量

    67 kDa

    基因ID

    51314

    UniProt

    Q8N427

    途径

    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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