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TXNDC3/NME8 抗体 (AA 1-446)

TXNDC3 适用: 人, 大鼠 ELISA, WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599402
发货至: 中国
  • 抗原 See all TXNDC3/NME8 (TXNDC3) 抗体
    TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-446
    适用
    • 21
    • 2
    • 2
    人, 大鼠
    宿主
    • 16
    • 4
    • 1
    克隆类型
    • 19
    • 2
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNDC3/NME8 antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    原理
    Anti-TXNDC3/NME8 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-TXNDC3-NME8 Antibody Picoband® (ABIN7599402). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human TXNDC3/NME8 recombinant protein (Position: M1-H446). Human TXNDC3/NME8 shares 63% and 61.2% amino acid (aa) sequence identity with mouse and rat TXNDC3/NME8, respectively.
    亚型
    IgG
    Top Product
    Discover our top product TXNDC3 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL
    1. Duriez, B., Duquesnoy, P., Escudier, E., Bridoux, A.-M., Escalier, D., Rayet, I., Marcos, E., Vojtek, A.-M., Bercher, J.-F., Amselem, S. A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia. Proc. Nat. Acad. Sci. 104: 3336-3341, 2007. Note: Erratum: Proc. Nat. Acad. Sci. 104: 6490 only, 2007. 2. Sadek, C. M., Damdimopoulos, A. E., Pelto-Huikko, M., Gustafsson, J.-A., Spyrou, G., Miranda-Vizuete, A. Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells. Genes Cells 6: 1077-1090, 2001.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    TXNDC3/NME8 (TXNDC3) (Thioredoxin Domain Containing 3 (TXNDC3))
    别名
    NME8 (TXNDC3 产品)
    背景

    Synonyms: NME8, SPTRX2, TXNDC3, Thioredoxin domain-containing protein 3, NM23-H8, NME/NM23 family member 8, Spermatid-specific thioredoxin-2, Sptrx-2

    Background: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.

    分子量
    67 kDa
    基因ID
    51314
    UniProt
    Q8N427
    途径
    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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