Exopolyphosphatase PRUNE1 (PRUNE1) (AA 1-444) 抗体
Quick Overview for Exopolyphosphatase PRUNE1 (PRUNE1) (AA 1-444) 抗体 (ABIN7599398)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-444
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原理
- Anti-PRUNE1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-PRUNE1 Antibody Picoband® (ABIN7599398). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRUNE1 recombinant protein (Position: M1-Q444).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alhaddad, B., Schossig, A., Haack, T. B., Kovacs-Nagy, R., Braunisch, M. C., Makowski, C., Senderek, J., Vill, K., Muller-Felber, W., Strom, T. M., Krabichler, B., Freisinger, P., and 17 others. PRUNE1 deficiency: expanding the clinical and genetic spectrum. Neuropediatrics 49: 330-338, 2018. 2. Costain, G., Shugar, A., Krishnan, P., Mahmutoglu, S., Laughlin, S., Kannu, P. Homozygous mutation in PRUNE1 in an Oji-Cree male with a complex neurological phenotype. Am. J. Med. Genet. 173A: 740-743, 2017. 3. Diana, D., Smaldone, G., De Antonellis, P., Pirone, L., Carotenuto, M., Alonzi, A., Di Gaetano, S., Zollo, M., Pedone, E. M., Fattorusso, R. Mapping functional interaction sites of human prune C-terminal domain by NMR spectroscopy in human cell lysates. Chemistry 19: 12217-12220, 2013. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Exopolyphosphatase PRUNE1 (PRUNE1)
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别名
- PRUNE1
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背景
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Synonyms: Protein Bop, BH3-only protein, Retrotransposon Gag-like protein 10, RTL10, BOP, C22orf29
Tissue Specificity: Ubiquitously expressed.
Background: This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants.
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分子量
- 60 kDa
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基因ID
- 58497
抗原
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