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Exopolyphosphatase PRUNE1 (PRUNE1) (AA 1-444) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in ELISA, IF, WB, FACS 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599398
发货至: 中国

Quick Overview for Exopolyphosphatase PRUNE1 (PRUNE1) (AA 1-444) 抗体 (ABIN7599398)

抗原

Exopolyphosphatase PRUNE1 (PRUNE1)

适用

人, 小鼠, 大鼠

宿主

  • 5

克隆类型

  • 5
多克隆

标记

  • 2
  • 1
  • 1
  • 1
非结合性

应用范围

ELISA, Immunofluorescence (IF), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

    AA 1-444

    原理

    Anti-PRUNE1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PRUNE1 Antibody Picoband® (ABIN7599398). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PRUNE1 recombinant protein (Position: M1-Q444).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Alhaddad, B., Schossig, A., Haack, T. B., Kovacs-Nagy, R., Braunisch, M. C., Makowski, C., Senderek, J., Vill, K., Muller-Felber, W., Strom, T. M., Krabichler, B., Freisinger, P., and 17 others. PRUNE1 deficiency: expanding the clinical and genetic spectrum. Neuropediatrics 49: 330-338, 2018. 2. Costain, G., Shugar, A., Krishnan, P., Mahmutoglu, S., Laughlin, S., Kannu, P. Homozygous mutation in PRUNE1 in an Oji-Cree male with a complex neurological phenotype. Am. J. Med. Genet. 173A: 740-743, 2017. 3. Diana, D., Smaldone, G., De Antonellis, P., Pirone, L., Carotenuto, M., Alonzi, A., Di Gaetano, S., Zollo, M., Pedone, E. M., Fattorusso, R. Mapping functional interaction sites of human prune C-terminal domain by NMR spectroscopy in human cell lysates. Chemistry 19: 12217-12220, 2013.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Exopolyphosphatase PRUNE1 (PRUNE1)

    别名

    PRUNE1

    背景

    Synonyms: Protein Bop, BH3-only protein, Retrotransposon Gag-like protein 10, RTL10, BOP, C22orf29

    Tissue Specificity: Ubiquitously expressed.

    Background: This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants.

    分子量

    60 kDa

    基因ID

    58497
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