CDR2 抗体 (AA 1-441)
Quick Overview for CDR2 抗体 (AA 1-441) (ABIN7599397)
抗原
See all CDR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-441
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原理
- Anti-CDR2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CDR2 Antibody Picoband® (ABIN7599397). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CDR2 recombinant protein (Position: M1-D441).
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亚型
- IgG
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anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (AA 296-404) antibody
CDR2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4F5 unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (AA 1-454) antibodyCDR2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (AA 296-404) antibodyCDR2 适用: 人 ELISA, WB, IHC (p), IF 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (N-Term) antibodyCDR2 适用: 人, 小鼠, 大鼠, 犬 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (AA 1-454) antibodyCDR2 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) antibodyCDR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (N-Term) antibodyCDR2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (N-Term) antibodyCDR2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) antibody (FITC)CDR2 适用: 人 ELISA, IHC, WB, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2) (AA 1-454) antibodyCDR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fletcher, C. F., Okano, H. J., Gilbert, D. J., Yang, Y., Yang, C., Copeland, N. G., Jenkins, N. A., Darnell, R. B. Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. Genomics 45: 313-319, 1997. 2. Furneaux, H. M., Rosenblum, M. K., Dalmau, J., Wong, E., Woodruff, P., Graus, F., Posner, J. B. Selective expression of Purkinje-cell antigens in tumor tissue from patients with paraneoplastic cerebellar degeneration. New Eng. J. Med. 322: 1844-1851, 1990. 3. Gress, T., Baldini, A., Rocchi, M., Furneaux, H., Posner, J. B., Siniscalco, M. In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR 2) to the region between two rare fragile sites of autosome 16 (16p12-p13.1). (Abstract) Cytogenet. Cell Genet. 58: 1999-2000, 1991. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))
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别名
- CDR2
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背景
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Synonyms: Cerebellar degeneration-related protein 2, Major Yo paraneoplastic antigen, Paraneoplastic cerebellar degeneration-associated antigen, CDR2, PCD17
Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Background: Cerebellar degeneration-related protein 2 is a protein that in humans is encoded by the CDR2 gene. By a combination of study of rodent/human somatic cell hybrids and in situ hybridization, this gene is assigned to 16p13.1-p12. The onconeuronal cerebellar degeneration-related antigen Cdr2 is associated with paraneoplastic syndromes. Neoplastic expression of Cdr2 in ovary and breast tumors triggers an autoimmune response that suppresses tumor growth by developing tumor immunity, but culminates in cerebellar degeneration when Cdr2-specific immune cells recognize neuronal Cdr2.
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分子量
- 62 kDa
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基因ID
- 1039
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UniProt
- Q01850
抗原
-
