CARD9 抗体 (AA 1-429)
Quick Overview for CARD9 抗体 (AA 1-429) (ABIN7599386)
抗原
See all CARD9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-429
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原理
- Anti-CARD9 Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CARD9 Picoband® Antibody (ABIN7599386). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CARD9 recombinant protein (Position: M1-D429).
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (AA 26-283) antibody
CARD9 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (AA 274-530) antibodyCARD9 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (AA 237-536) antibodyCARD9 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (AA 521-536) antibodyCARD9 适用: 人, 猴 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (AA 1-492) antibodyCARD9 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (C-Term) antibodyCARD9 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (AA 467-516) antibodyCARD9 适用: 人, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) (Middle Region) antibodyCARD9 适用: 人, 小鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 9 (CARD9) antibodyCARD9 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hsu, Y.-M. S., Zhang, Y., You, Y., Wang, D., Li, H., Duramad, O., Qin, X.-F., Dong, C., Lin, X. The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nature Immun. 8: 198-205, 2007. 2. Lanternier, F., Pathan, S., Vincent, Q. B., Liu, L., Cypowyj, S., Prando, C., Migaud, M., Taibi, L., Ammar-Khodja, A., Boudghene Stambouli, O., Guellil, B., Jacobs, F., and 21 others. Deep dermatophytosis and inherited CARD9 deficiency. New Eng. J. Med. 369: 1704-1714, 2013. 3. Yang, H., Minamishima, Y. A., Yan, Q., Schlisio, S., Ebert, B. L., Zhang, X., Zhang, L., Kim, W. Y., Olumi, A. F., Kaelin, W. G., Jr. pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappa-B agonist Card9 by CK2. Molec. Cell 28: 15-27, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
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别名
- CARD9
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背景
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Synonyms: Caspase recruitment domain-containing protein 9. Hcard9. CARD9
Tissue Specificity: Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Background: Caspase recruitment domain-containing protein 9 is an adaptor protein of the CARD-CC protein family, which in humans is encoded by the CARD9 gene. It is mapped to 9q34.3. The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
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分子量
- 63 kDa
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基因ID
- 64170
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UniProt
- Q9H257
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途径
- Activation of Innate immune Response
抗原
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