Trnt1 抗体 (AA 1-410)
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- 抗原 See all Trnt1 抗体
- Trnt1 (tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1))
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抗原表位
- AA 1-410
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Trnt1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 原理
- Anti-TRNT1 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-TRNT1 Antibody Picoband® (ABIN7599365). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human TRNT1 recombinant protein (Position: M1-Q410).
- 亚型
- IgG
- Top Product
- Discover our top product Trnt1 Primary Antibody
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anti-tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) (AA 1-405) antibody
Trnt1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) (AA 1-405) antibodyTrnt1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) (AA 75-124) antibodyTrnt1 适用: 人, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) (N-Term) antibodyTrnt1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) (AA 128-293) antibodyTrnt1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) (AA 135-434) antibodyTrnt1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) (N-Term) antibodyTrnt1 适用: 人, 兔, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chakraborty, P. K., Schmitz-Abe, K., Kennedy, E. K., Mamady, H., Naas, T., Durie, D., Campagna, D. R., Lau, A., Sendamarai, A. K., Wiseman, D. H., May, A., Jolles, S., and 23 others. Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD). Blood 124: 2867-2871, 2014. 2. DeLuca, A. P., Whitmore, S. S., Barnes, J., Sharma, T. P., Westfall, T. A., Scott, C. A., Weed, M. C., Wiley, J. S., Wiley, L. A., Johnston, R. M., Schnieders, M. J., Lentz, S. R., Tucker, B. A., Mullins, R. F., Scheetz, T. E., Stone, E. M., Slusarski, D. C. Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. Hum. Molec. Genet. 25: 44-56, 2016. 3. Lizano, E., Schuster, J., Muller, M., Kelso, J., Morl, M. A splice variant of the human CCA-adding enzyme with modified activity. J. Molec. Biol. 366: 1258-1265, 2007. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- Trnt1 (tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1))
- 别名
- TRNT1 (Trnt1 产品)
- 背景
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Synonyms: Tricarboxylate transport protein, mitochondrial, Citrate transport protein, CTP, Solute carrier family 25 member 1, Tricarboxylate carrier protein, SLC25A1, SLC20A3
Tissue Specificity: Detected in brain. Detected at very much lower levels in heart, lung, placenta and skeletal muscle. Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
Background: tRNA-nucleotidyltransferase 1, is an enzyme that in humans is encoded by the TRNT1 gene. The protein encoded by this gene is a CCA-adding enzyme which belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. This essential enzyme functions by catalyzing the addition of the conserved nucleotide triplet CCA to the 3' terminus of tRNA molecules. Mutations in this gene result in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Alternative splicing results in multiple transcript variants.
- 分子量
- 50 kDa
- 基因ID
- 51095
- UniProt
- Q96Q11
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