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NOB1 抗体 (AA 1-389)

This anti-NOB1 antibody is a 兔 多克隆 antibody detecting NOB1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599344
发货至: 中国

Quick Overview for NOB1 抗体 (AA 1-389) (ABIN7599344)

抗原

See all NOB1 抗体
NOB1 (RNA-Binding Protein NOB1 (NOB1))

适用

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人, 小鼠, 大鼠

宿主

  • 49
  • 2

克隆类型

  • 49
  • 2
多克隆

标记

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  • 1
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This NOB1 antibody is un-conjugated

应用范围

  • 41
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 9
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-389

    原理

    Anti-NOB1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-NOB1 Antibody Picoband® (ABIN7599344). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NOB1 recombinant protein (Position: M1-D389).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Ameismeier, M., Cheng, J., Berninghausen, O., Beckmann, R. Visualizing late states of human 40S ribosomal subunit maturation. Nature 558: 249-253, 2018. 2. Fatica, A., Oeffinger, M., Dlakic, M., Tollervey, D. Nob1p is required for cleavage of the 3-prime end of 18S rRNA. Molec. Cell. Biol. 23: 1798-1807, 2003. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/6/2010.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    NOB1 (RNA-Binding Protein NOB1 (NOB1))

    别名

    NOB1

    背景

    Synonyms: Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, T-cell translocation protein 2, LMO2, RBTN2, RBTNL1, RHOM2, TTG2

    Background: RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene. In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.

    分子量

    47 kDa

    基因ID

    28987

    途径

    Protein targeting to Nucleus
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