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NSUN4 抗体 (AA 1-379)

NSUN4 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599331
发货至: 中国
  • 抗原 See all NSUN4 抗体
    NSUN4 (NOL1/NOP2/Sun Domain Family, Member 4 (NSUN4))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    AA 1-379
    适用
    • 18
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 17
    • 1
    克隆类型
    • 18
    多克隆
    标记
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NSUN4 antibody is un-conjugated
    应用范围
    • 7
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB)
    原理
    Anti-NSUN4 Antibody Picoband®
    产品特性
    Anti-NSUN4 Antibody Picoband® (ABIN7599331). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human NSUN4 recombinant protein (Position: M1-K379). Human NSUN4 shares 86.3% amino acid (aa) sequence identity with mouse NSUN4.
    Top Product
    Discover our top product NSUN4 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Camara, Y., Asin-Cayuela, J., Park, C. B., Metodiev, M. D., Shi, Y., Ruzzenente, B., Kukat, C., Habermann, B., Wibom, R., Hultenby, K., Franz, T., Erdjument-Bromage, H., Tempst, P., Hallberg, B. M., Gustafsson, C. M., Larsson, N.-G. MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome. Cell Metab. 13: 527-539, 2011. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 8/30/2013. 3. Spahr, H., Habermann, B., Gustafsson, C. M., Larsson, N.-G., Hallberg, B. M. Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis. Proc. Nat. Acad. Sci. 109: 15253-15258, 2012.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    NSUN4 (NOL1/NOP2/Sun Domain Family, Member 4 (NSUN4))
    别名
    NSUN4 (NSUN4 产品)
    背景
    NSUN4 belongsto a family of RNA 5-methylcytosine (m5C) methyltransferases(MTases).MTERF4 recruits NSUN4 to the large ribosomal subunit in a process crucial for mitochondrial ribosome biogenesis. NSUN4 is a dual function protein, which on the one hand is needed for 12S rRNA methylation, and on the other hand interacts withMTERF4 to facilitate mitoribosomal assembly. The calculatedMWof NSUN4 is 43 kDa, 29786-1-AP can detect the band around 40 kDa.
    分子量
    40 kDa
    基因ID
    387338
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