LYAR 抗体 (AA 1-379)
Quick Overview for LYAR 抗体 (AA 1-379) (ABIN7599330)
抗原
See all LYAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-379
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原理
- Anti-LYAR Antibody Picoband®
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产品特性
- Anti-LYAR Antibody Picoband® (ABIN7599330). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LYAR recombinant protein (Position: M1-K379). Human LYAR shares 71.9% and 73.7% amino acid (aa) sequence identity with mouse and rat LYAR, respectively.
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anti-Ly1 Antibody Reactive (LYAR) (AA 270-388) antibody
LYAR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 1-379) antibodyLYAR 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 10-160) antibodyLYAR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 1-379) antibodyLYAR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 288-379) antibodyLYAR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 271-386) antibodyLYAR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) antibodyLYAR 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 179-228) antibodyLYAR WB 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (Internal Region) antibodyLYAR 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 81-130) antibodyLYAR 适用: 人, 小鼠, 大鼠, 马, 豚鼠, 兔, 斑马鱼, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 9/21/2017. 2. Ju, J., Wang, Y., Liu, R., Zhang, Y., Xu, Z., Wang, Y., Wu, Y., Liu, M., Cerruti, L., Zou, F., Ma, C., Fang, M., Tan, R., Jane, S. M., Zhao, Q. Human fetal globin gene expression is regulated by LYAR. Nucleic Acids Res. 42: 9740-9752, 2014. 3. Su, L., Hershberger, R. J., Weissman, I. L. LYAR, a novel nucleolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation. Genes Dev. 7: 735-748, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- LYAR (Ly1 Antibody Reactive (LYAR))
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别名
- LYAR
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物质类
- Antibody
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背景
- Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene (Ly-1 antibody reactive clone). LYAR (Ly-1/CD5 antibody reactive clone) is a 45-50 kDa nucleolar protein that was named for the ability of its antibody to cross-react with Ly-1. Its function is unclear, it is known to associate with MYCN and RRP1B, the latter association giving rise to the suggestion that LYAR is involved with RNA metabolism. Human LYAR is 379 amino acids (aa) in length. It contains two C2H2-type Zn finger regions (aa 6-25 and 33-51) followed by one coiled-coil region (aa 175-219) and an NLS (aa 217-222). There are multiple Zn-binding sites and three utilized phosphorylation sites at Ser244, Ser258 and Ser276. Over aa 288-379, human LYAR shares 75 % aa identity with mouse LYAR.
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分子量
- 44 kDa
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基因ID
- 55646
抗原
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