Pellino 3 抗体 (AA 1-375)
Quick Overview for Pellino 3 抗体 (AA 1-375) (ABIN7599324)
抗原
See all Pellino 3 (PELI3) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 1-375
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                                            原理
- Anti-PELI3 Antibody Picoband®
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                                            交叉反应 (详细)
- No cross reactivity with other proteins.
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                                            产品特性
- Anti-PELI3 Antibody Picoband® (ABIN7599324). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            纯化方法
- Immunogen affinity purified.
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                                            免疫原
- E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.
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                                            亚型
- IgG
 
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                                            应用备注
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                        Western blot, 0.25-0.5 μg/mL, Mouse, Rat
 Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
 Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 ELISA, 0.1-0.5 μg/mL, -
 1. Butler, M. P., Hanly, J. A., Moynagh, P. N. Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner. J. Biol. Chem. 280: 27759-27768, 2005. 2. Jensen, L. E., Whitehead, A. S. Pellino3, a novel member of the pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein. J. Immun. 171: 1500-1506, 2003.
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            浓度
- 500 μg/mL
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                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
 
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    - Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))
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                                            别名
- PELI3
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                                            背景
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                        Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody Tissue Specificity: Expressed in all tissues. Background: The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcript variants encoding different isoforms have been found for this gene. 
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                                            分子量
- 51 kDa
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                                            基因ID
- 246330
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                                            UniProt
- Q8N2H9
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                                            途径
- Toll-Like Receptors Cascades
 抗原
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