PANX1 抗体 (AA 1-362)
Quick Overview for PANX1 抗体 (AA 1-362) (ABIN7599312)
抗原
See all PANX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-362
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原理
- Anti-Pannexin 1/PANX1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Pannexin 1/PANX1 Antibody Picoband® (ABIN7599312). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Pannexin 1/PANX1 recombinant protein (Position: M1-D362).
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亚型
- IgG
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anti-Pannexin 1 (PANX1) (AA 77-260) antibody
PANX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 1 (PANX1) (Middle Region) antibodyPANX1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 1 (PANX1) (AA 228-411) antibodyPANX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 1 (PANX1) (AA 288-426) antibodyPANX1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 1 (PANX1) (AA 327-425) antibodyPANX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Pannexin 1 (PANX1) (AA 231-280) antibodyPANX1 适用: 人, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 1 (PANX1) (AA 297-426) antibodyPANX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 1 (PANX1) antibodyPANX1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Pannexin 1 (PANX1) (Middle Region) antibodyPANX1 适用: 哺乳动物 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 1 (PANX1) (Internal Region) antibodyPANX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bruzzone, R., Hormuzdi, S. G., Barbe, M. T., Herb, A., Monyer, H. Pannexins, a family of gap junction proteins expressed in brain. Proc. Nat. Acad. Sci. 100: 13644-13649, 2003. 2. Chekeni, F. B., Elliott, M. R., Sandilos, J. K., Walk, S. F., Kinchen, J. M., Lazarowski, E. R., Armstrong, A. J., Penuela, S., Laird, D. W., Salvesen, G. S., Isakson, B. E., Bayliss, D. A., Ravichandran, K. S. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature 467: 863-867, 2010. 3. Gross, M. B. Personal Communication. Baltimore, Md. 11/30/2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PANX1 (Pannexin 1 (PANX1))
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别名
- PANX1
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背景
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Synonyms: CD59A glycoprotein, MAC-inhibitory protein, MAC-IP, Membrane attack complex inhibition factor, MACIF, Protectin, CD59, Cd59a, Cd59
Tissue Specificity: Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A-431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. Abundant in breast carcinoma cell lines. In the colonic mucosa, expressed in epithelia but not in the connective tissue of the lamina propria. In the thyroid gland, expressed in the epithelium of the thyroid follicles. In pancreas, expressed in the islets of Langerhans cells, but not in the surrounding epithelial cells of the exocrine pancreas. In kidney, expressed in the epithelia of the distal tubules. Not expressed in connective tissue, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin.
Background: Pannexin 1 is a protein in humans that is encoded by the PANX1 gene. The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
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分子量
- 48 kDa
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基因ID
- 24145
抗原
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