Snurportin 1 抗体 (AA 1-360)
Quick Overview for Snurportin 1 抗体 (AA 1-360) (ABIN7599310)
抗原
See all Snurportin 1 (SNUPN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-360
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原理
- Anti-SNURPORTIN1/SNUPN Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SNURPORTIN1/SNUPN Antibody Picoband® (ABIN7599310). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SNURPORTIN1/SNUPN recombinant protein (Position: M1-N360).
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亚型
- IgG
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anti-Snurportin 1 (SNUPN) (AA 1-329) antibody
SNUPN 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snurportin 1 (SNUPN) (AA 1-360) antibodySNUPN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Snurportin 1 (SNUPN) (AA 1-360) antibodySNUPN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B2-1B4 unconjugated
anti-Snurportin 1 (SNUPN) (AA 1-360) antibodySNUPN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snurportin 1 (SNUPN) (AA 24-73) antibodySNUPN 适用: 人, 大鼠, Cow, 马, Pig, 豚鼠, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Snurportin 1 (SNUPN) (AA 287-336) antibodySNUPN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Snurportin 1 (SNUPN) (AA 1-249) antibodySNUPN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dong, X., Biswas, A., Suel, K. E., Jackson, L. K., Martinez, R., Gu, H., Chook, Y. M. Structural basis for leucine-rich nuclear export signal recognition by CRM1. Nature 458: 1136-1141, 2009. Note: Erratum: Nature 461: 550 only, 2009. 2. Huber, J., Cronshagen, U., Kadokura, M., Marshallsay, C., Wada, T., Sekine, M., Luhrmann, R. Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure. EMBO J. 17: 4114-4126, 1998. 3. Monecke, T., Guttler, T., Neumann, P., Dickmanns, A., Gorlich, D., Ficner, R. Crystal structure of the nuclear export receptor CRM1 in complex with snurportin 1 and RanGTP. Science 324: 1087-1091, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Snurportin 1 (SNUPN)
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别名
- SNUPN
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背景
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Synonyms: Protein Hook homolog 3, h-hook3, Hhk3, HOOK3
Tissue Specificity: Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).
Background: Snurportin1 is a protein that in humans is encoded by the SNUPN gene. The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
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分子量
- 41 kDa
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基因ID
- 10073
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UniProt
- O95149
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途径
- Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus
抗原
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